Quality of sleep in escitalopram-treated female patients with panic disorder.
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| Title: | Quality of sleep in escitalopram-treated female patients with panic disorder. |
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| Authors: | Todder, D., Baune, B. T. |
| Source: | Human Psychopharmacology: Clinical & Experimental. Mar2010, Vol. 25 Issue 2, p167-173. 7p. 3 Charts. |
| Subjects: | Panic disorders, Antipsychotic agents, Sleep, Mental depression, Anxiety, Psychoses, Psychology of women |
| Abstract: | Objective The purpose of this study was to assess the development of the night-activity rhythm and quality of sleep during escitalopram treatment of patients suffering from panic disorder. Methods Fifteen women with panic disorder were included and followed-up over a 5-week study period during treatment with escitalopram. An age-matched control group of 15 women were also assessed for 1 week. Motor activity was continuously measured with an electronic wrist device (Actiwatch), sleep was assessed with the Pittsburgh sleep quality index (PSQI) and patients were clinically assessed with the panic and agoraphobic scale (P&A), the global assessment of functioning (GAF) score, the Hamilton depression and anxiety scales (HAM-D, HAM-A) and the clinical global impression (CGI) score. Results There was a statistically significant difference on the self-rated PSQI between the panic disorder patients and the control group. This difference disappeared after 4 weeks of treatment with escitalopram. There was no statistically significant difference of the objective measurements of the Actiwatch between the patients and the control group. In addition, no statistically significant changes were found in the actigraphy measurements at the beginning and the end of the treatment period for patients with panic disorder. Conclusions Patients with panic disorder rate their sleep worse than healthy controls. Treatment with escitalopram improved the subjective quality of sleep, whereas objective measures remained unchanged during treatment. Copyright © 2010 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR] |
| Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 48434035 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Quality of sleep in escitalopram-treated female patients with panic disorder. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Todder%2C+D%2E%22">Todder, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Baune%2C+B%2E+T%2E%22">Baune, B. T.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Human+Psychopharmacology%3A+Clinical+%26+Experimental%22">Human Psychopharmacology: Clinical & Experimental</searchLink>. Mar2010, Vol. 25 Issue 2, p167-173. 7p. 3 Charts. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Panic+disorders%22">Panic disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Antipsychotic+agents%22">Antipsychotic agents</searchLink><br /><searchLink fieldCode="DE" term="%22Sleep%22">Sleep</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Anxiety%22">Anxiety</searchLink><br /><searchLink fieldCode="DE" term="%22Psychoses%22">Psychoses</searchLink><br /><searchLink fieldCode="DE" term="%22Psychology+of+women%22">Psychology of women</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Objective The purpose of this study was to assess the development of the night-activity rhythm and quality of sleep during escitalopram treatment of patients suffering from panic disorder. Methods Fifteen women with panic disorder were included and followed-up over a 5-week study period during treatment with escitalopram. An age-matched control group of 15 women were also assessed for 1 week. Motor activity was continuously measured with an electronic wrist device (Actiwatch), sleep was assessed with the Pittsburgh sleep quality index (PSQI) and patients were clinically assessed with the panic and agoraphobic scale (P&A), the global assessment of functioning (GAF) score, the Hamilton depression and anxiety scales (HAM-D, HAM-A) and the clinical global impression (CGI) score. Results There was a statistically significant difference on the self-rated PSQI between the panic disorder patients and the control group. This difference disappeared after 4 weeks of treatment with escitalopram. There was no statistically significant difference of the objective measurements of the Actiwatch between the patients and the control group. In addition, no statistically significant changes were found in the actigraphy measurements at the beginning and the end of the treatment period for patients with panic disorder. Conclusions Patients with panic disorder rate their sleep worse than healthy controls. Treatment with escitalopram improved the subjective quality of sleep, whereas objective measures remained unchanged during treatment. Copyright © 2010 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Human Psychopharmacology: Clinical & Experimental is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=48434035 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/hup.1088 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 167 Subjects: – SubjectFull: Panic disorders Type: general – SubjectFull: Antipsychotic agents Type: general – SubjectFull: Sleep Type: general – SubjectFull: Mental depression Type: general – SubjectFull: Anxiety Type: general – SubjectFull: Psychoses Type: general – SubjectFull: Psychology of women Type: general Titles: – TitleFull: Quality of sleep in escitalopram-treated female patients with panic disorder. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Todder, D. – PersonEntity: Name: NameFull: Baune, B. T. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: Mar2010 Type: published Y: 2010 Identifiers: – Type: issn-print Value: 08856222 Numbering: – Type: volume Value: 25 – Type: issue Value: 2 Titles: – TitleFull: Human Psychopharmacology: Clinical & Experimental Type: main |
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