Genetics of developmental dyslexia.
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| Title: | Genetics of developmental dyslexia. |
|---|---|
| Authors: | Scerri, Thomas S., Schulte-Körne, Gerd |
| Source: | European Child & Adolescent Psychiatry. Mar2010, Vol. 19 Issue 3, p179-197. 19p. 5 Diagrams, 5 Charts, 1 Graph. |
| Subjects: | Dyslexia, Learning disability genetics, Reading disability, Heredity, School children |
| Abstract: | Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in school-aged children. Linkage studies have identified numerous loci throughout the genome that are likely to harbour candidate dyslexia susceptibility genes. Association studies and the refinement of chromosomal translocation break points in individuals with dyslexia have resulted in the discovery of candidate genes at some of these loci. A key function of many of these genes is their involvement in neuronal migration. This complements anatomical abnormalities discovered in dyslexic brains, such as ectopias, that may be the result of irregular neuronal migration. [ABSTRACT FROM AUTHOR] |
| Copyright of European Child & Adolescent Psychiatry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 48586680 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Genetics of developmental dyslexia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Scerri%2C+Thomas+S%2E%22">Scerri, Thomas S.</searchLink><br /><searchLink fieldCode="AR" term="%22Schulte-Körne%2C+Gerd%22">Schulte-Körne, Gerd</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Child+%26+Adolescent+Psychiatry%22">European Child & Adolescent Psychiatry</searchLink>. Mar2010, Vol. 19 Issue 3, p179-197. 19p. 5 Diagrams, 5 Charts, 1 Graph. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Dyslexia%22">Dyslexia</searchLink><br /><searchLink fieldCode="DE" term="%22Learning+disability+genetics%22">Learning disability genetics</searchLink><br /><searchLink fieldCode="DE" term="%22Reading+disability%22">Reading disability</searchLink><br /><searchLink fieldCode="DE" term="%22Heredity%22">Heredity</searchLink><br /><searchLink fieldCode="DE" term="%22School+children%22">School children</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in school-aged children. Linkage studies have identified numerous loci throughout the genome that are likely to harbour candidate dyslexia susceptibility genes. Association studies and the refinement of chromosomal translocation break points in individuals with dyslexia have resulted in the discovery of candidate genes at some of these loci. A key function of many of these genes is their involvement in neuronal migration. This complements anatomical abnormalities discovered in dyslexic brains, such as ectopias, that may be the result of irregular neuronal migration. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Child & Adolescent Psychiatry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=48586680 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00787-009-0081-0 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 19 StartPage: 179 Subjects: – SubjectFull: Dyslexia Type: general – SubjectFull: Learning disability genetics Type: general – SubjectFull: Reading disability Type: general – SubjectFull: Heredity Type: general – SubjectFull: School children Type: general Titles: – TitleFull: Genetics of developmental dyslexia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Scerri, Thomas S. – PersonEntity: Name: NameFull: Schulte-Körne, Gerd IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: Mar2010 Type: published Y: 2010 Identifiers: – Type: issn-print Value: 10188827 Numbering: – Type: volume Value: 19 – Type: issue Value: 3 Titles: – TitleFull: European Child & Adolescent Psychiatry Type: main |
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