Outcome of suicidal patients with schizophrenia: results from a naturalistic study.

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Title: Outcome of suicidal patients with schizophrenia: results from a naturalistic study.
Authors: Schennach‐Wolff, R. (AUTHOR), Jäger, M. (AUTHOR), Seemüller, F. (AUTHOR), Obermeier, M. (AUTHOR), Schmauss, M. (AUTHOR), Laux, G. (AUTHOR), Pfeiffer, H. (AUTHOR), Naber, D. (AUTHOR), Schmidt, L. G. (AUTHOR), Gaebel, W. (AUTHOR), Klosterkötter, J. (AUTHOR), Heuser, I. (AUTHOR), Maier, W. (AUTHOR), Lemke, M. R. (AUTHOR), Rüther, E. (AUTHOR), Klingberg, S. (AUTHOR), Gastpar, M. (AUTHOR), Möller, H.‐J. (AUTHOR), Riedel, M. (AUTHOR)
Source: Acta Psychiatrica Scandinavica. May2010, Vol. 121 Issue 5, p359-370. 12p. 1 Diagram, 5 Charts, 2 Graphs.
Subjects: Schizophrenia, Mental illness, Suicidal behavior, Hamilton Depression Inventory, Diagnosis of mental depression, Schizotypal personality disorder
Abstract: Schennach-Wolff R, Jäger M, Seemüller F, Obermeier M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller H-J, Riedel M. Outcome of suicidal patients with schizophrenia: results from a naturalistic study. Objective: Purpose was to assess suicidality before and at the time of admission in patients with schizophrenia and compare outcome differences. Method: Biweekly PANSS (Positive and Negative Syndrome Scale), HAMD (Hamilton Depression Rating Scale) and UKU (Udvalg for Klinske Undersogelser Side Effect Rating Scale) ratings were evaluated in 339 in-patients with schizophrenic spectrum disorders. Response was defined as an initial 20% PANSS total score reduction at discharge, remission was defined according to the proposed consensus criteria by the Remission in Schizophrenia Working Group. Results: Suicidal patients (22%) scored significantly higher on the PANSS negative subscore, PANSS insight item and HAMD total score at admission and at discharge. They developed significantly more side effects. No differences were found concerning response and remission between the two patient subgroups. Conclusion: Despite receiving significantly more antidepressants the suicidal patients suffered from significantly more depressive symptoms up to discharge, yet without differing regarding response and remission. [ABSTRACT FROM AUTHOR]
Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Outcome of suicidal patients with schizophrenia: results from a naturalistic study.
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  Data: <searchLink fieldCode="AR" term="%22Schennach‐Wolff%2C+R%2E%22">Schennach‐Wolff, R.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jäger%2C+M%2E%22">Jäger, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Seemüller%2C+F%2E%22">Seemüller, F.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Obermeier%2C+M%2E%22">Obermeier, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Schmauss%2C+M%2E%22">Schmauss, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Laux%2C+G%2E%22">Laux, G.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Pfeiffer%2C+H%2E%22">Pfeiffer, H.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Naber%2C+D%2E%22">Naber, D.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Schmidt%2C+L%2E+G%2E%22">Schmidt, L. G.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gaebel%2C+W%2E%22">Gaebel, W.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Klosterkötter%2C+J%2E%22">Klosterkötter, J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Heuser%2C+I%2E%22">Heuser, I.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Maier%2C+W%2E%22">Maier, W.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lemke%2C+M%2E+R%2E%22">Lemke, M. R.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rüther%2C+E%2E%22">Rüther, E.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Klingberg%2C+S%2E%22">Klingberg, S.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gastpar%2C+M%2E%22">Gastpar, M.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Möller%2C+H%2E‐J%2E%22">Möller, H.‐J.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Riedel%2C+M%2E%22">Riedel, M.</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Acta+Psychiatrica+Scandinavica%22">Acta Psychiatrica Scandinavica</searchLink>. May2010, Vol. 121 Issue 5, p359-370. 12p. 1 Diagram, 5 Charts, 2 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Schizophrenia%22">Schizophrenia</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+illness%22">Mental illness</searchLink><br /><searchLink fieldCode="DE" term="%22Suicidal+behavior%22">Suicidal behavior</searchLink><br /><searchLink fieldCode="DE" term="%22Hamilton+Depression+Inventory%22">Hamilton Depression Inventory</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnosis+of+mental+depression%22">Diagnosis of mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Schizotypal+personality+disorder%22">Schizotypal personality disorder</searchLink>
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  Data: Schennach-Wolff R, Jäger M, Seemüller F, Obermeier M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller H-J, Riedel M. Outcome of suicidal patients with schizophrenia: results from a naturalistic study. Objective: Purpose was to assess suicidality before and at the time of admission in patients with schizophrenia and compare outcome differences. Method: Biweekly PANSS (Positive and Negative Syndrome Scale), HAMD (Hamilton Depression Rating Scale) and UKU (Udvalg for Klinske Undersogelser Side Effect Rating Scale) ratings were evaluated in 339 in-patients with schizophrenic spectrum disorders. Response was defined as an initial 20% PANSS total score reduction at discharge, remission was defined according to the proposed consensus criteria by the Remission in Schizophrenia Working Group. Results: Suicidal patients (22%) scored significantly higher on the PANSS negative subscore, PANSS insight item and HAMD total score at admission and at discharge. They developed significantly more side effects. No differences were found concerning response and remission between the two patient subgroups. Conclusion: Despite receiving significantly more antidepressants the suicidal patients suffered from significantly more depressive symptoms up to discharge, yet without differing regarding response and remission. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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