Craniocervical dystonia: clinical and pathophysiological features.

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Bibliographic Details
Title: Craniocervical dystonia: clinical and pathophysiological features.
Authors: Colosimo, C., Suppa, A., Fabbrini, G., Bologna, M., Berardelli, A.
Source: European Journal of Neurology. Jul2010 Supplement 1, Vol. 17, p15-21. 7p.
Subjects: Dystonia, Eyelid diseases, Movement disorders, Muscle cramps, Posture disorders, Sensory disorders, Basal ganglia
Abstract: Blepharospasm, oromandibular, lingual, laryngeal and cervical dystonia are common forms of adult-onset dystonia. Each condition may appear in isolation or manifest along with other forms of craniocervical dystonia. Although the various craniocervical dystonias typically present with involuntary muscle spasms causing abnormal postures, they differ for some clinical features. Neurophysiologic and neuroimaging studies have shown a number of motor and sensory abnormalities at cortical and subcortical levels, probably reflecting a dysfunction in the basal ganglia–thalamo-cortical circuits. The best treatment for craniocervical dystonia is botulinum toxin injected into the overactive muscles. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
Description
Abstract:Blepharospasm, oromandibular, lingual, laryngeal and cervical dystonia are common forms of adult-onset dystonia. Each condition may appear in isolation or manifest along with other forms of craniocervical dystonia. Although the various craniocervical dystonias typically present with involuntary muscle spasms causing abnormal postures, they differ for some clinical features. Neurophysiologic and neuroimaging studies have shown a number of motor and sensory abnormalities at cortical and subcortical levels, probably reflecting a dysfunction in the basal ganglia–thalamo-cortical circuits. The best treatment for craniocervical dystonia is botulinum toxin injected into the overactive muscles. [ABSTRACT FROM AUTHOR]
ISSN:13515101
DOI:10.1111/j.1468-1331.2010.03045.x