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Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial.

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Title: Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial.
Authors: Diamant, Michaela, Van Gaal, Luc, Stranks, Stephen, Northrup, Justin, Dachuang Cao, Taylor, Kristin, Trautmann, Michael
Source: Lancet. 6/26/2010, Vol. 375 Issue 9733, p2234-2243. 10p. 1 Diagram, 4 Charts, 5 Graphs.
Subjects: Randomized controlled trials, Insulin therapy, Glucose, Glycosylated hemoglobin, Type 2 diabetes, Hypoglycemia, Weight loss
Abstract: The article offers information on an open-label randomized study which compared the efficacy of exenatide with insulin glargine titrated to glucose targets in lowering hemoglobin A1c. The study subjects, which involved adults with type 2 diabetes who had suboptimum glycaemic control, were randomly assigned to add exenatide or insulin glargine to their blood-glucose lowering regimens. Presented in details are the findings of the study. It concludes that exenatide is ideal for patients whose risk for hypoglycemia, weight loss and convenience are particular concerns.
Database: Psychology and Behavioral Sciences Collection
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Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 51818059
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial.
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  Data: <searchLink fieldCode="AR" term="%22Diamant%2C+Michaela%22">Diamant, Michaela</searchLink><br /><searchLink fieldCode="AR" term="%22Van+Gaal%2C+Luc%22">Van Gaal, Luc</searchLink><br /><searchLink fieldCode="AR" term="%22Stranks%2C+Stephen%22">Stranks, Stephen</searchLink><br /><searchLink fieldCode="AR" term="%22Northrup%2C+Justin%22">Northrup, Justin</searchLink><br /><searchLink fieldCode="AR" term="%22Dachuang+Cao%22">Dachuang Cao</searchLink><br /><searchLink fieldCode="AR" term="%22Taylor%2C+Kristin%22">Taylor, Kristin</searchLink><br /><searchLink fieldCode="AR" term="%22Trautmann%2C+Michael%22">Trautmann, Michael</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 6/26/2010, Vol. 375 Issue 9733, p2234-2243. 10p. 1 Diagram, 4 Charts, 5 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Insulin+therapy%22">Insulin therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Glucose%22">Glucose</searchLink><br /><searchLink fieldCode="DE" term="%22Glycosylated+hemoglobin%22">Glycosylated hemoglobin</searchLink><br /><searchLink fieldCode="DE" term="%22Type+2+diabetes%22">Type 2 diabetes</searchLink><br /><searchLink fieldCode="DE" term="%22Hypoglycemia%22">Hypoglycemia</searchLink><br /><searchLink fieldCode="DE" term="%22Weight+loss%22">Weight loss</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: The article offers information on an open-label randomized study which compared the efficacy of exenatide with insulin glargine titrated to glucose targets in lowering hemoglobin A1c. The study subjects, which involved adults with type 2 diabetes who had suboptimum glycaemic control, were randomly assigned to add exenatide or insulin glargine to their blood-glucose lowering regimens. Presented in details are the findings of the study. It concludes that exenatide is ideal for patients whose risk for hypoglycemia, weight loss and convenience are particular concerns.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=51818059
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/S0140-6736(10)60406-0
    Languages:
      – Code: eng
        Text: English
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        PageCount: 10
        StartPage: 2234
    Subjects:
      – SubjectFull: Randomized controlled trials
        Type: general
      – SubjectFull: Insulin therapy
        Type: general
      – SubjectFull: Glucose
        Type: general
      – SubjectFull: Glycosylated hemoglobin
        Type: general
      – SubjectFull: Type 2 diabetes
        Type: general
      – SubjectFull: Hypoglycemia
        Type: general
      – SubjectFull: Weight loss
        Type: general
    Titles:
      – TitleFull: Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial.
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            NameFull: Van Gaal, Luc
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            NameFull: Northrup, Justin
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            NameFull: Dachuang Cao
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            NameFull: Taylor, Kristin
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            NameFull: Trautmann, Michael
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            – D: 26
              M: 06
              Text: 6/26/2010
              Type: published
              Y: 2010
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              Value: 01406736
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              Value: 375
            – Type: issue
              Value: 9733
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