The prevalence and phenomenology of self-injurious and aggressive behaviour in genetic syndromes.
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| Title: | The prevalence and phenomenology of self-injurious and aggressive behaviour in genetic syndromes. |
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| Authors: | Arron, K. (AUTHOR), Oliver, C. (AUTHOR), Moss, J. (AUTHOR), Berg, K. (AUTHOR), Burbidge, C. (AUTHOR) |
| Source: | Journal of Intellectual Disability Research. Feb2011, Vol. 55 Issue 2, p109-120. 12p. 5 Charts. |
| Subjects: | Dwarfism, Affect (Psychology), Aggression (Psychology), Analysis of variance, Angelman syndrome, Autism, Chi-squared test, Chromosome abnormalities, Comparative studies, Fragile X syndrome, Intellectual disabilities, People with intellectual disabilities, Prader-Willi syndrome, Scale analysis (Psychology), Self-mutilation, U-statistics, Disease prevalence, Cri-du-chat syndrome |
| Geographic Terms: | United Kingdom |
| Abstract: | Self-injurious and aggressive behaviours are reported as components of some behavioural phenotypes but there are few studies comparing across syndrome groups. In this study we examined the prevalence of these behaviours and the associated person characteristics in seven genetic syndromes. Questionnaire data on self-injury and aggression, mood, hyperactivity, autism spectrum disorder and repetitive behaviour were collected on Angelman (AS, n = 104), Cornelia de Lange (CdLS, 101), Cri du Chat (CdCS, 58), Fragile X (FXS, 191), Lowe (LS, 56), Prader-Willi (PWS, 189) and Smith-Magenis (SMS, 42) syndromes. A significantly higher prevalence of self-injury was evident in CdCS, CdLS, FXS, PWS, LS and SMS. The prevalence of aggression was significantly heightened in AS and SMS. Self-injury was associated with repetitive and impulsive behaviour in CdLS, FXS, PWS and LS. Impulsivity and overactivity were significantly higher in those showing aggression across all syndrome groups. These data quantify the risk for self-injury and aggression in the syndromes studied with implications for early intervention. The associations between these behaviours and person characteristics both within and between syndromes warrant further research. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Intellectual Disability Research is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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