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The association of personality disorders with the prospective 7-year course of anxiety disorders.

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Title: The association of personality disorders with the prospective 7-year course of anxiety disorders.
Authors: Ansell, E. B., Pinto, A., Edelen, M. O., Markowitz, J. C., Sanislow, C. A., Yen, S., Zanarini, M., Skodol, A. E., Shea, M. T., Morey, L. C., Gunderson, J. G., McGlashan, T. H., Grilo, C. M.
Source: Psychological Medicine. May2011, Vol. 41 Issue 5, p1019-1028. 10p. 3 Charts, 2 Graphs.
Subjects: Analysis of variance, Computer software, Interviewing, Longitudinal method, Research methodology, Obsessive-compulsive disorder, Personality disorders, Phobias, Post-traumatic stress disorder, Pathological psychology, Research funding, Statistical hypothesis testing, Statistics, Disease relapse, Sample size (Statistics), Data analysis, Anxiety disorders, Disease remission, Proportional hazards models
Abstract: BackgroundThis study prospectively examined the natural clinical course of six anxiety disorders over 7 years of follow-up in individuals with personality disorders (PDs) and/or major depressive disorder. Rates of remission, relapse, new episode onset and chronicity of anxiety disorders were examined for specific associations with PDs.MethodParticipants were 499 patients with anxiety disorders in the Collaborative Longitudinal Personality Disorders Study, who were assessed with structured interviews for psychiatric disorders at yearly intervals throughout 7 years of follow-up. These data were used to determine probabilities of changes in disorder status for social phobia (SP), generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), panic disorder and panic disorder with agoraphobia.ResultsEstimated remission rates for anxiety disorders in this study group ranged from 73% to 94%. For those patients who remitted from an anxiety disorder, relapse rates ranged from 34% to 67%. Rates for new episode onsets of anxiety disorders ranged from 3% to 17%. Specific PDs demonstrated associations with remission, relapse, new episode onsets and chronicity of anxiety disorders. Associations were identified between schizotypal PD with course of SP, PTSD and GAD; avoidant PD with course of SP and OCD; obsessive-compulsive PD with course of GAD, OCD, and agoraphobia; and borderline PD with course of OCD, GAD and panic with agoraphobia.ConclusionsFindings suggest that specific PD diagnoses have negative prognostic significance for the course of anxiety disorders underscoring the importance of assessing and considering PD diagnoses in patients with anxiety disorders. [ABSTRACT FROM PUBLISHER]
Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: The association of personality disorders with the prospective 7-year course of anxiety disorders.
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  Data: <searchLink fieldCode="AR" term="%22Ansell%2C+E%2E+B%2E%22">Ansell, E. B.</searchLink><br /><searchLink fieldCode="AR" term="%22Pinto%2C+A%2E%22">Pinto, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Edelen%2C+M%2E+O%2E%22">Edelen, M. O.</searchLink><br /><searchLink fieldCode="AR" term="%22Markowitz%2C+J%2E+C%2E%22">Markowitz, J. C.</searchLink><br /><searchLink fieldCode="AR" term="%22Sanislow%2C+C%2E+A%2E%22">Sanislow, C. A.</searchLink><br /><searchLink fieldCode="AR" term="%22Yen%2C+S%2E%22">Yen, S.</searchLink><br /><searchLink fieldCode="AR" term="%22Zanarini%2C+M%2E%22">Zanarini, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Skodol%2C+A%2E+E%2E%22">Skodol, A. E.</searchLink><br /><searchLink fieldCode="AR" term="%22Shea%2C+M%2E+T%2E%22">Shea, M. T.</searchLink><br /><searchLink fieldCode="AR" term="%22Morey%2C+L%2E+C%2E%22">Morey, L. C.</searchLink><br /><searchLink fieldCode="AR" term="%22Gunderson%2C+J%2E+G%2E%22">Gunderson, J. G.</searchLink><br /><searchLink fieldCode="AR" term="%22McGlashan%2C+T%2E+H%2E%22">McGlashan, T. H.</searchLink><br /><searchLink fieldCode="AR" term="%22Grilo%2C+C%2E+M%2E%22">Grilo, C. M.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Psychological+Medicine%22">Psychological Medicine</searchLink>. May2011, Vol. 41 Issue 5, p1019-1028. 10p. 3 Charts, 2 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22Analysis+of+variance%22">Analysis of variance</searchLink><br /><searchLink fieldCode="DE" term="%22Computer+software%22">Computer software</searchLink><br /><searchLink fieldCode="DE" term="%22Interviewing%22">Interviewing</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink><br /><searchLink fieldCode="DE" term="%22Research+methodology%22">Research methodology</searchLink><br /><searchLink fieldCode="DE" term="%22Obsessive-compulsive+disorder%22">Obsessive-compulsive disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Personality+disorders%22">Personality disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Phobias%22">Phobias</searchLink><br /><searchLink fieldCode="DE" term="%22Post-traumatic+stress+disorder%22">Post-traumatic stress disorder</searchLink><br /><searchLink fieldCode="DE" term="%22Pathological+psychology%22">Pathological psychology</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Statistical+hypothesis+testing%22">Statistical hypothesis testing</searchLink><br /><searchLink fieldCode="DE" term="%22Statistics%22">Statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+relapse%22">Disease relapse</searchLink><br /><searchLink fieldCode="DE" term="%22Sample+size+%28Statistics%29%22">Sample size (Statistics)</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis%22">Data analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Anxiety+disorders%22">Anxiety disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+remission%22">Disease remission</searchLink><br /><searchLink fieldCode="DE" term="%22Proportional+hazards+models%22">Proportional hazards models</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: BackgroundThis study prospectively examined the natural clinical course of six anxiety disorders over 7 years of follow-up in individuals with personality disorders (PDs) and/or major depressive disorder. Rates of remission, relapse, new episode onset and chronicity of anxiety disorders were examined for specific associations with PDs.MethodParticipants were 499 patients with anxiety disorders in the Collaborative Longitudinal Personality Disorders Study, who were assessed with structured interviews for psychiatric disorders at yearly intervals throughout 7 years of follow-up. These data were used to determine probabilities of changes in disorder status for social phobia (SP), generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), panic disorder and panic disorder with agoraphobia.ResultsEstimated remission rates for anxiety disorders in this study group ranged from 73% to 94%. For those patients who remitted from an anxiety disorder, relapse rates ranged from 34% to 67%. Rates for new episode onsets of anxiety disorders ranged from 3% to 17%. Specific PDs demonstrated associations with remission, relapse, new episode onsets and chronicity of anxiety disorders. Associations were identified between schizotypal PD with course of SP, PTSD and GAD; avoidant PD with course of SP and OCD; obsessive-compulsive PD with course of GAD, OCD, and agoraphobia; and borderline PD with course of OCD, GAD and panic with agoraphobia.ConclusionsFindings suggest that specific PD diagnoses have negative prognostic significance for the course of anxiety disorders underscoring the importance of assessing and considering PD diagnoses in patients with anxiety disorders. [ABSTRACT FROM PUBLISHER]
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  Data: <i>Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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