Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change.
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| Title: | Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change. |
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| Authors: | Cysique, LucetteA. (AUTHOR), Franklin, Donald (AUTHOR), Abramson, Ian (AUTHOR), Ellis, RonaldJ. (AUTHOR), Letendre, Scott (AUTHOR), Collier, Ann (AUTHOR), Clifford, David (AUTHOR), Gelman, Benjamin (AUTHOR), McArthur, Justin (AUTHOR), Morgello, Susan (AUTHOR), Simpson, David (AUTHOR), McCutchan, J. Allen (AUTHOR), Grant, Igor (AUTHOR), Heaton, RobertK. (AUTHOR), the CHARTER group (AUTHOR), the HNRC group (AUTHOR) |
| Source: | Journal of Clinical & Experimental Neuropsychology. Jun2011, Vol. 33 Issue 5, p505-522. 18p. 15 Charts, 2 Graphs. |
| Subjects: | Cognition disorders, Central nervous system, Cognitive ability, Neuropsychological tests, Regression analysis |
| Abstract: | Reliable detection and quantification of longitudinal cognitive change are of considerable importance in many neurological disorders, particularly to monitor central nervous system effects of disease progression and treatment. In the current study, we developed normative data for repeated neuropsychological (NP) assessments (6 testings) using a modified standard regression-based (SRB) approach in a sample that includes both HIV-uninfected (HIV-, N = 172) and neuromedically stable HIV-infected (HIV+, N = 124) individuals. Prior analyses indicated no differences in NP change between the infected and uninfected participants. The norms for change included correction for factors found to significantly affect follow-up performance, using hierarchical regression. The most robust and consistent predictors of follow-up performance were the prior performance on the same test (which contributed in all models) and a measure of prior overall NP competence (predictor in 97% of all models). Demographic variables were predictors in 10-46% of all models and in small amounts; while test-retest interval contributed in only 6% of all models. Based on the regression equations, standardized change scores (z scores) were computed for each test measure at each interval; these z scores were then averaged to create a total battery change score. An independent sample of HIV- participants who had completed 8 of the 15 tests was used to validate an abridged summary change score. The normative data are available in an electronic format by e-mail request to the first author. Correction for practice effects based on normative data improved the consistency of NP impairment classification in a clinically stable longitudinal cohort after baseline. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Clinical & Experimental Neuropsychology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 60911338 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Cysique%2C+LucetteA%2E%22">Cysique, LucetteA.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Franklin%2C+Donald%22">Franklin, Donald</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Abramson%2C+Ian%22">Abramson, Ian</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ellis%2C+RonaldJ%2E%22">Ellis, RonaldJ.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Letendre%2C+Scott%22">Letendre, Scott</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Collier%2C+Ann%22">Collier, Ann</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Clifford%2C+David%22">Clifford, David</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gelman%2C+Benjamin%22">Gelman, Benjamin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22McArthur%2C+Justin%22">McArthur, Justin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Morgello%2C+Susan%22">Morgello, Susan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Simpson%2C+David%22">Simpson, David</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22McCutchan%2C+J%2E+Allen%22">McCutchan, J. Allen</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Grant%2C+Igor%22">Grant, Igor</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Heaton%2C+RobertK%2E%22">Heaton, RobertK.</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22the+CHARTER+group%22">the CHARTER group</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22the+HNRC+group%22">the HNRC group</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Clinical+%26+Experimental+Neuropsychology%22">Journal of Clinical & Experimental Neuropsychology</searchLink>. Jun2011, Vol. 33 Issue 5, p505-522. 18p. 15 Charts, 2 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Cognition+disorders%22">Cognition disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Central+nervous+system%22">Central nervous system</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+ability%22">Cognitive ability</searchLink><br /><searchLink fieldCode="DE" term="%22Neuropsychological+tests%22">Neuropsychological tests</searchLink><br /><searchLink fieldCode="DE" term="%22Regression+analysis%22">Regression analysis</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Reliable detection and quantification of longitudinal cognitive change are of considerable importance in many neurological disorders, particularly to monitor central nervous system effects of disease progression and treatment. In the current study, we developed normative data for repeated neuropsychological (NP) assessments (6 testings) using a modified standard regression-based (SRB) approach in a sample that includes both HIV-uninfected (HIV-, N = 172) and neuromedically stable HIV-infected (HIV+, N = 124) individuals. Prior analyses indicated no differences in NP change between the infected and uninfected participants. The norms for change included correction for factors found to significantly affect follow-up performance, using hierarchical regression. The most robust and consistent predictors of follow-up performance were the prior performance on the same test (which contributed in all models) and a measure of prior overall NP competence (predictor in 97% of all models). Demographic variables were predictors in 10-46% of all models and in small amounts; while test-retest interval contributed in only 6% of all models. Based on the regression equations, standardized change scores (z scores) were computed for each test measure at each interval; these z scores were then averaged to create a total battery change score. An independent sample of HIV- participants who had completed 8 of the 15 tests was used to validate an abridged summary change score. The normative data are available in an electronic format by e-mail request to the first author. Correction for practice effects based on normative data improved the consistency of NP impairment classification in a clinically stable longitudinal cohort after baseline. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Clinical & Experimental Neuropsychology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1080/13803395.2010.535504 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 18 StartPage: 505 Subjects: – SubjectFull: Cognition disorders Type: general – SubjectFull: Central nervous system Type: general – SubjectFull: Cognitive ability Type: general – SubjectFull: Neuropsychological tests Type: general – SubjectFull: Regression analysis Type: general Titles: – TitleFull: Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cysique, LucetteA. – PersonEntity: Name: NameFull: Franklin, Donald – PersonEntity: Name: NameFull: Abramson, Ian – PersonEntity: Name: NameFull: Ellis, RonaldJ. – PersonEntity: Name: NameFull: Letendre, Scott – PersonEntity: Name: NameFull: Collier, Ann – PersonEntity: Name: NameFull: Clifford, David – PersonEntity: Name: NameFull: Gelman, Benjamin – PersonEntity: Name: NameFull: McArthur, Justin – PersonEntity: Name: NameFull: Morgello, Susan – PersonEntity: Name: NameFull: Simpson, David – PersonEntity: Name: NameFull: McCutchan, J. Allen – PersonEntity: Name: NameFull: Grant, Igor – PersonEntity: Name: NameFull: Heaton, RobertK. – PersonEntity: Name: NameFull: the CHARTER group – PersonEntity: Name: NameFull: the HNRC group IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2011 Type: published Y: 2011 Identifiers: – Type: issn-print Value: 13803395 Numbering: – Type: volume Value: 33 – Type: issue Value: 5 Titles: – TitleFull: Journal of Clinical & Experimental Neuropsychology Type: main |
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