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The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.

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Title: The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Authors: Baigent, Colin, Landray, Martin J., Reith, Christina, Emberson, Jonathan, Wheeler, David C., Tomson, Charles, Wanner, Christoph, Krane, Vera, Cass, Alan, Craig, Jonathan, Neal, Bruce, Lixin Jiang, Lai Seong Hooi, Levin, Adeera, Agodoa, Lawrence, Gaziano, Mike, Kasiske, Bertram, Walker, Robert, Massy, Ziad A., Feldt-Rasmussen, Bo
Source: Lancet. 6/25/2011, Vol. 377 Issue 9784, p2181-2192. 12p.
Subjects: Low density lipoproteins, Cholesterol, Ezetimibe, Placebos, Atherosclerosis
Abstract: The article offers information on the effect of lowering low-density lipoprotein (LDL) cholesterol with simvastatin and ezetimibe, in patients with chronic kidney disease, with the Study of Heart and Renal Protection (SHARP) trial. It states that 4650 patients received simvastatin and ezetimibe, while 4620 received placebo. It mentions that there was a reduction in LDL cholesterol, with reduction in atherosclerotic events.
Database: Psychology and Behavioral Sciences Collection
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  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 62079689
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
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  Data: The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
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  Data: <searchLink fieldCode="AR" term="%22Baigent%2C+Colin%22">Baigent, Colin</searchLink><br /><searchLink fieldCode="AR" term="%22Landray%2C+Martin+J%2E%22">Landray, Martin J.</searchLink><br /><searchLink fieldCode="AR" term="%22Reith%2C+Christina%22">Reith, Christina</searchLink><br /><searchLink fieldCode="AR" term="%22Emberson%2C+Jonathan%22">Emberson, Jonathan</searchLink><br /><searchLink fieldCode="AR" term="%22Wheeler%2C+David+C%2E%22">Wheeler, David C.</searchLink><br /><searchLink fieldCode="AR" term="%22Tomson%2C+Charles%22">Tomson, Charles</searchLink><br /><searchLink fieldCode="AR" term="%22Wanner%2C+Christoph%22">Wanner, Christoph</searchLink><br /><searchLink fieldCode="AR" term="%22Krane%2C+Vera%22">Krane, Vera</searchLink><br /><searchLink fieldCode="AR" term="%22Cass%2C+Alan%22">Cass, Alan</searchLink><br /><searchLink fieldCode="AR" term="%22Craig%2C+Jonathan%22">Craig, Jonathan</searchLink><br /><searchLink fieldCode="AR" term="%22Neal%2C+Bruce%22">Neal, Bruce</searchLink><br /><searchLink fieldCode="AR" term="%22Lixin+Jiang%22">Lixin Jiang</searchLink><br /><searchLink fieldCode="AR" term="%22Lai+Seong+Hooi%22">Lai Seong Hooi</searchLink><br /><searchLink fieldCode="AR" term="%22Levin%2C+Adeera%22">Levin, Adeera</searchLink><br /><searchLink fieldCode="AR" term="%22Agodoa%2C+Lawrence%22">Agodoa, Lawrence</searchLink><br /><searchLink fieldCode="AR" term="%22Gaziano%2C+Mike%22">Gaziano, Mike</searchLink><br /><searchLink fieldCode="AR" term="%22Kasiske%2C+Bertram%22">Kasiske, Bertram</searchLink><br /><searchLink fieldCode="AR" term="%22Walker%2C+Robert%22">Walker, Robert</searchLink><br /><searchLink fieldCode="AR" term="%22Massy%2C+Ziad+A%2E%22">Massy, Ziad A.</searchLink><br /><searchLink fieldCode="AR" term="%22Feldt-Rasmussen%2C+Bo%22">Feldt-Rasmussen, Bo</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 6/25/2011, Vol. 377 Issue 9784, p2181-2192. 12p.
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  Data: <searchLink fieldCode="DE" term="%22Low+density+lipoproteins%22">Low density lipoproteins</searchLink><br /><searchLink fieldCode="DE" term="%22Cholesterol%22">Cholesterol</searchLink><br /><searchLink fieldCode="DE" term="%22Ezetimibe%22">Ezetimibe</searchLink><br /><searchLink fieldCode="DE" term="%22Placebos%22">Placebos</searchLink><br /><searchLink fieldCode="DE" term="%22Atherosclerosis%22">Atherosclerosis</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The article offers information on the effect of lowering low-density lipoprotein (LDL) cholesterol with simvastatin and ezetimibe, in patients with chronic kidney disease, with the Study of Heart and Renal Protection (SHARP) trial. It states that 4650 patients received simvastatin and ezetimibe, while 4620 received placebo. It mentions that there was a reduction in LDL cholesterol, with reduction in atherosclerotic events.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=62079689
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      – Type: doi
        Value: 10.1016/S0140-6736(11)60739-3
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      – Code: eng
        Text: English
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        PageCount: 12
        StartPage: 2181
    Subjects:
      – SubjectFull: Low density lipoproteins
        Type: general
      – SubjectFull: Cholesterol
        Type: general
      – SubjectFull: Ezetimibe
        Type: general
      – SubjectFull: Placebos
        Type: general
      – SubjectFull: Atherosclerosis
        Type: general
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      – TitleFull: The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
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              Text: 6/25/2011
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