Bacteria and Pathogenesis of Human Salivary Calculus.

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Bibliographic Details
Title: Bacteria and Pathogenesis of Human Salivary Calculus.
Authors: Teymoortash, Afshin, Wollstein, Ana C., Lippert, Burkard M., Peldszus, Roswitha, Werner, Jochen A.
Source: Acta Oto-Laryngologica. Mar2002, Vol. 122 Issue 2, p210-214. 5p.
Subjects: Calculi, Salivary gland diseases
Abstract: The exact cause of salivary calculus formation is unknown and the aim of this study was to ascertain whether bacteria play a role. Sialoliths from nine patients with chronic obstructive sialadenitis of the submandibular gland were analysed. Bacterial gene fragments were amplified from DNA extracted from salivary calculi by means of polymerase chain reaction using a universal bacterial primer pair. Comparative 16S ribosomal RNA sequence analysis was used for identification. We detected and identified oral bacteria (predominantly Streptococcus species) in all samples. The present results suggest a potential role for bacteria in the etiopathogenesis of sialolithiasis. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
Description
Abstract:The exact cause of salivary calculus formation is unknown and the aim of this study was to ascertain whether bacteria play a role. Sialoliths from nine patients with chronic obstructive sialadenitis of the submandibular gland were analysed. Bacterial gene fragments were amplified from DNA extracted from salivary calculi by means of polymerase chain reaction using a universal bacterial primer pair. Comparative 16S ribosomal RNA sequence analysis was used for identification. We detected and identified oral bacteria (predominantly Streptococcus species) in all samples. The present results suggest a potential role for bacteria in the etiopathogenesis of sialolithiasis. [ABSTRACT FROM AUTHOR]
ISSN:00016489
DOI:10.1080/00016480252814252