Neurocognitive performance in first-episode and chronic schizophrenic patients.
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| Title: | Neurocognitive performance in first-episode and chronic schizophrenic patients. |
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| Authors: | Moritz, Steffen, Andresen, Burghard, Perro, Christian, PERSIST Study Group, Schickel, Marc, Krausz, Michael, Naber, Dieter |
| Source: | European Archives of Psychiatry & Clinical Neuroscience. 2002, Vol. 252 Issue 1, p33. 5p. |
| Subjects: | People with schizophrenia, Cognition disorders, Neurodegeneration |
| Abstract: | Previous research on neuropsychological disturbances in first-episode and chronic schizophrenic patients has provided mixed results which can be partially attributed to methodological inconsistencies. For the present study, 70 schizophrenic patients (40 with chronic and 30 with first-episode schizophrenia) were compared to 30 healthy controls on a large battery of neuropsychological tests. Special attention was paid to potential confounds such as differences in psychopathology, age and educational level between the schizophrenic sub-samples.Healthy controls performed better than both first-episode and chronic patients in almost all cognitive domains (P < 0.01), while the patient samples did not differ in any of the tasks. Results were confirmed in a second series of analyses in which patient subgroups were equated for sociodemographic background variables. The present results confirm recent data collected in longitudinal studies, thus, lending further support for a neurodevelopmental model of schizophrenia. It is suggested that neuropsychological disturbances occur early in schizophrenia and do not worsen in the course beyond age-related decrement. Possible reasons why previous research has produced contradictory findings are discussed. [ABSTRACT FROM AUTHOR] |
| Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 6447001 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=6447001 |
| RecordInfo | BibRecord: BibEntity: Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 33 Subjects: – SubjectFull: People with schizophrenia Type: general – SubjectFull: Cognition disorders Type: general – SubjectFull: Neurodegeneration Type: general Titles: – TitleFull: Neurocognitive performance in first-episode and chronic schizophrenic patients. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Moritz, Steffen – PersonEntity: Name: NameFull: Andresen, Burghard – PersonEntity: Name: NameFull: Perro, Christian – PersonEntity: Name: NameFull: PERSIST Study Group – PersonEntity: Name: NameFull: Schickel, Marc – PersonEntity: Name: NameFull: Krausz, Michael – PersonEntity: Name: NameFull: Naber, Dieter IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: 2002 Type: published Y: 2002 Identifiers: – Type: issn-print Value: 09401334 Numbering: – Type: volume Value: 252 – Type: issue Value: 1 Titles: – TitleFull: European Archives of Psychiatry & Clinical Neuroscience Type: main |
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