Muscle morphology, self-reported physical activity and insulin resistance syndrome.
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| Title: | Muscle morphology, self-reported physical activity and insulin resistance syndrome. |
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| Authors: | Hedman, A., Byberg, L., Reneland, R., Lithell, H. O. |
| Source: | Acta Physiologica Scandinavica. Aug2002, Vol. 175 Issue 4, p325-332. 8p. |
| Subjects: | Muscles, Morphology, Insulin resistance, Blood lipids |
| Abstract: | ABSTRACT In a population-based sample of 475 men the associations between muscle morphology, self-reported physical activity (PA) and insulin resistance (IR) syndrome were investigated. Also, we studied to what degree muscle morphology contributes to the association between PA and IR syndrome. Muscle morphology and the components of IR syndrome were compared in four groups categorized according to self-reported habitual PA data. We found a significantly higher percentage of type I fibres, fibre area and number of capillaries around the fibres and a lower proportion of type IIB fibres with higher level of PA. The relative distribution of type I fibres and capillarization were positively related to high density lipoprotein (HDL) cholesterol and negatively to serum triglycerides (TG) and plasminogen activator inhibitor-1 (PAI-1) activity. The percentage of type IIB fibres was were inversely related to HDL cholesterol and positively to serum TG, PAI-1 activity and resting heart rate. Insulin sensitivity was positively and independently related to PA level (P < 0.001). Regression analysis including all relevant variables regarding insulin sensitivity indicated that the significant explanatory variables left in the equation were body mass index (BMI), glucose intolerance, PAI-1 activity, serum free fatty acid concentration, proportion of type IIB fibres, HDL cholesterol level, drug treatment, PA level, and waist-to-hip ratio, which together explained 55% of the variation in the insulin sensitivity index. In conclusion, both fibre type distribution and muscle capillary density might contribute to the beneficial effect of PA on IR syndrome. [ABSTRACT FROM AUTHOR] |
| Copyright of Acta Physiologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 7122829 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Muscle morphology, self-reported physical activity and insulin resistance syndrome. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Hedman%2C+A%2E%22">Hedman, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Byberg%2C+L%2E%22">Byberg, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Reneland%2C+R%2E%22">Reneland, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Lithell%2C+H%2E+O%2E%22">Lithell, H. O.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Acta+Physiologica+Scandinavica%22">Acta Physiologica Scandinavica</searchLink>. Aug2002, Vol. 175 Issue 4, p325-332. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Muscles%22">Muscles</searchLink><br /><searchLink fieldCode="DE" term="%22Morphology%22">Morphology</searchLink><br /><searchLink fieldCode="DE" term="%22Insulin+resistance%22">Insulin resistance</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+lipids%22">Blood lipids</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: ABSTRACT In a population-based sample of 475 men the associations between muscle morphology, self-reported physical activity (PA) and insulin resistance (IR) syndrome were investigated. Also, we studied to what degree muscle morphology contributes to the association between PA and IR syndrome. Muscle morphology and the components of IR syndrome were compared in four groups categorized according to self-reported habitual PA data. We found a significantly higher percentage of type I fibres, fibre area and number of capillaries around the fibres and a lower proportion of type IIB fibres with higher level of PA. The relative distribution of type I fibres and capillarization were positively related to high density lipoprotein (HDL) cholesterol and negatively to serum triglycerides (TG) and plasminogen activator inhibitor-1 (PAI-1) activity. The percentage of type IIB fibres was were inversely related to HDL cholesterol and positively to serum TG, PAI-1 activity and resting heart rate. Insulin sensitivity was positively and independently related to PA level (P < 0.001). Regression analysis including all relevant variables regarding insulin sensitivity indicated that the significant explanatory variables left in the equation were body mass index (BMI), glucose intolerance, PAI-1 activity, serum free fatty acid concentration, proportion of type IIB fibres, HDL cholesterol level, drug treatment, PA level, and waist-to-hip ratio, which together explained 55% of the variation in the insulin sensitivity index. In conclusion, both fibre type distribution and muscle capillary density might contribute to the beneficial effect of PA on IR syndrome. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Acta Physiologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=7122829 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1046/j.1365-201X.2002.01000.x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 325 Subjects: – SubjectFull: Muscles Type: general – SubjectFull: Morphology Type: general – SubjectFull: Insulin resistance Type: general – SubjectFull: Blood lipids Type: general Titles: – TitleFull: Muscle morphology, self-reported physical activity and insulin resistance syndrome. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hedman, A. – PersonEntity: Name: NameFull: Byberg, L. – PersonEntity: Name: NameFull: Reneland, R. – PersonEntity: Name: NameFull: Lithell, H. O. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: Aug2002 Type: published Y: 2002 Identifiers: – Type: issn-print Value: 00016772 Numbering: – Type: volume Value: 175 – Type: issue Value: 4 Titles: – TitleFull: Acta Physiologica Scandinavica Type: main |
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