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Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): a phase 3 open-label, random ised controlled trial.

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Title: Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): a phase 3 open-label, random ised controlled trial.
Authors: Yung-Jue Bang, Young-Woo Kim, Han-Kwang Yang, Hyun Cheol Chung, Young-Kyu Park, Kyung Hee Lee, Keun-Wook Lee, Yong Ho Kim, Sang-Ik Noh, Joe Yong Cho, Young Joe Mok, Yeul Hong Kim, Jiafu Ji, Ta-Sen Yeh, Button, Peter, Sirzén, Florin, Sung Hoon Noh
Source: Lancet. 1/28/2012, Vol. 379 Issue 9813, p315-321. 7p.
Subjects: Adjuvant treatment of cancer, Oxaliplatin, Germfree life, Survival analysis (Biometry), Gastrectomy, Stomach cancer patients
Abstract: The article presents a study which examines the effect of adjuvant chemotherapy with capecitabine plus oxaliplatin in the disease-free survival following D2 gastrectomy. The study randomly subjected stage II-IIIB gastric cancer patients, who undergone curative D2 gastrectomy, to adjuvant chemotherapy with oral capecitabine and intravenous oxaliplatin treatment or surgery only. Result shows that chemotherapy patients have 74% of 3 year disease-free survival, while surgery only patients show 59%.
Database: Psychology and Behavioral Sciences Collection
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  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 71344488
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Label: Title
  Group: Ti
  Data: Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): a phase 3 open-label, random ised controlled trial.
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  Label: Authors
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  Data: <searchLink fieldCode="AR" term="%22Yung-Jue+Bang%22">Yung-Jue Bang</searchLink><br /><searchLink fieldCode="AR" term="%22Young-Woo+Kim%22">Young-Woo Kim</searchLink><br /><searchLink fieldCode="AR" term="%22Han-Kwang+Yang%22">Han-Kwang Yang</searchLink><br /><searchLink fieldCode="AR" term="%22Hyun+Cheol+Chung%22">Hyun Cheol Chung</searchLink><br /><searchLink fieldCode="AR" term="%22Young-Kyu+Park%22">Young-Kyu Park</searchLink><br /><searchLink fieldCode="AR" term="%22Kyung+Hee+Lee%22">Kyung Hee Lee</searchLink><br /><searchLink fieldCode="AR" term="%22Keun-Wook+Lee%22">Keun-Wook Lee</searchLink><br /><searchLink fieldCode="AR" term="%22Yong+Ho+Kim%22">Yong Ho Kim</searchLink><br /><searchLink fieldCode="AR" term="%22Sang-Ik+Noh%22">Sang-Ik Noh</searchLink><br /><searchLink fieldCode="AR" term="%22Joe+Yong+Cho%22">Joe Yong Cho</searchLink><br /><searchLink fieldCode="AR" term="%22Young+Joe+Mok%22">Young Joe Mok</searchLink><br /><searchLink fieldCode="AR" term="%22Yeul+Hong+Kim%22">Yeul Hong Kim</searchLink><br /><searchLink fieldCode="AR" term="%22Jiafu+Ji%22">Jiafu Ji</searchLink><br /><searchLink fieldCode="AR" term="%22Ta-Sen+Yeh%22">Ta-Sen Yeh</searchLink><br /><searchLink fieldCode="AR" term="%22Button%2C+Peter%22">Button, Peter</searchLink><br /><searchLink fieldCode="AR" term="%22Sirzén%2C+Florin%22">Sirzén, Florin</searchLink><br /><searchLink fieldCode="AR" term="%22Sung+Hoon+Noh%22">Sung Hoon Noh</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 1/28/2012, Vol. 379 Issue 9813, p315-321. 7p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Adjuvant+treatment+of+cancer%22">Adjuvant treatment of cancer</searchLink><br /><searchLink fieldCode="DE" term="%22Oxaliplatin%22">Oxaliplatin</searchLink><br /><searchLink fieldCode="DE" term="%22Germfree+life%22">Germfree life</searchLink><br /><searchLink fieldCode="DE" term="%22Survival+analysis+%28Biometry%29%22">Survival analysis (Biometry)</searchLink><br /><searchLink fieldCode="DE" term="%22Gastrectomy%22">Gastrectomy</searchLink><br /><searchLink fieldCode="DE" term="%22Stomach+cancer+patients%22">Stomach cancer patients</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The article presents a study which examines the effect of adjuvant chemotherapy with capecitabine plus oxaliplatin in the disease-free survival following D2 gastrectomy. The study randomly subjected stage II-IIIB gastric cancer patients, who undergone curative D2 gastrectomy, to adjuvant chemotherapy with oral capecitabine and intravenous oxaliplatin treatment or surgery only. Result shows that chemotherapy patients have 74% of 3 year disease-free survival, while surgery only patients show 59%.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=71344488
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/S0140-6736(11)61873-4
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 7
        StartPage: 315
    Subjects:
      – SubjectFull: Adjuvant treatment of cancer
        Type: general
      – SubjectFull: Oxaliplatin
        Type: general
      – SubjectFull: Germfree life
        Type: general
      – SubjectFull: Survival analysis (Biometry)
        Type: general
      – SubjectFull: Gastrectomy
        Type: general
      – SubjectFull: Stomach cancer patients
        Type: general
    Titles:
      – TitleFull: Adjuvant capecitabine and oxaliplatin for gastric cancer after D2 gastrectomy (CLASSIC): a phase 3 open-label, random ised controlled trial.
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              M: 01
              Text: 1/28/2012
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