Diagnosis and treatment of giant cell granuloma of the temporal bone: Report of eight cases.

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Title: Diagnosis and treatment of giant cell granuloma of the temporal bone: Report of eight cases.
Authors: Ma, Yueying (AUTHOR), Liu, Liangfa (AUTHOR), Huang, Deliang (AUTHOR), Han, Dongyi (AUTHOR), Wang, Jialing (AUTHOR), Wu, Wenming (AUTHOR), Zhao, Jiandong (AUTHOR), Liu, Mingbo (AUTHOR), Song, Zhigang (AUTHOR), Oghagbon, Efosa Kenneth (AUTHOR), Yang, Shiming (AUTHOR)
Source: Acta Oto-Laryngologica. Jun2012, Vol. 132 Issue 6, p657-662. 6p. 3 Color Photographs, 3 Black and White Photographs, 2 Charts.
Subjects: Temporal bone surgery, Audiometry, Digital subtraction angiography, Earache, Giant cell tumors, Granuloma, Hearing disorders, Magnetic resonance imaging, Otoscopy, Operative surgery, Tinnitus, Tomography, Descriptive statistics, Diagnosis
Geographic Terms: China
Abstract: Conclusions: It is impossible to make a diagnosis of temporal giant cell granuloma (GCG) before operation because of nonspecific clinical and imaging feature. Surgery is the first-line choice of treatment. Objective: To evaluate the diagnosis and treatment of temporal GCG. Methods: Eight patients with GCG receiving treatment in the Chinese PLA General Hospital between 2001 and 2010 were recruited for the study. These patients' clinical features, imaging and histopathological findings, types of surgery, and results of follow-up evaluations were noted. Results: The group was made up of four males and four females, with a median age of 37 years (range 21-50 years). Four patients had a granuloma on the left side and four on the right of the head. The median duration of the disease was 21 months (range 5-60 months). All patients, except one referred to us for recurring disease, were managed in our hospital. The main symptoms were: hearing loss ( n = 5), tinnitus ( n = 4), otalgia ( n = 3), dizziness ( n = 2), and local masses ( n = 2). Radiological examination of the masses revealed erosion of the temporal bone and base of the skull. There was no definitive diagnosis in any of the patients before surgery. All patients had surgical treatment, six of them by middle cranial fossa approach and two by combined cranio-auricular approach. Surgical complications included partial facial paralysis (three cases) and cerebral edema (one case) but they resolved soon after surgery. One patient was lost to follow-up, but the other seven were followed up over a mean period of 24 months; none has reported a recurrence. [ABSTRACT FROM AUTHOR]
Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
  Group: Ti
  Data: Diagnosis and treatment of giant cell granuloma of the temporal bone: Report of eight cases.
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  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Ma%2C+Yueying%22">Ma, Yueying</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Liangfa%22">Liu, Liangfa</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Huang%2C+Deliang%22">Huang, Deliang</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Han%2C+Dongyi%22">Han, Dongyi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wang%2C+Jialing%22">Wang, Jialing</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wu%2C+Wenming%22">Wu, Wenming</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zhao%2C+Jiandong%22">Zhao, Jiandong</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Liu%2C+Mingbo%22">Liu, Mingbo</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Song%2C+Zhigang%22">Song, Zhigang</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Oghagbon%2C+Efosa+Kenneth%22">Oghagbon, Efosa Kenneth</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Shiming%22">Yang, Shiming</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Acta+Oto-Laryngologica%22">Acta Oto-Laryngologica</searchLink>. Jun2012, Vol. 132 Issue 6, p657-662. 6p. 3 Color Photographs, 3 Black and White Photographs, 2 Charts.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Temporal+bone+surgery%22">Temporal bone surgery</searchLink><br /><searchLink fieldCode="DE" term="%22Audiometry%22">Audiometry</searchLink><br /><searchLink fieldCode="DE" term="%22Digital+subtraction+angiography%22">Digital subtraction angiography</searchLink><br /><searchLink fieldCode="DE" term="%22Earache%22">Earache</searchLink><br /><searchLink fieldCode="DE" term="%22Giant+cell+tumors%22">Giant cell tumors</searchLink><br /><searchLink fieldCode="DE" term="%22Granuloma%22">Granuloma</searchLink><br /><searchLink fieldCode="DE" term="%22Hearing+disorders%22">Hearing disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Otoscopy%22">Otoscopy</searchLink><br /><searchLink fieldCode="DE" term="%22Operative+surgery%22">Operative surgery</searchLink><br /><searchLink fieldCode="DE" term="%22Tinnitus%22">Tinnitus</searchLink><br /><searchLink fieldCode="DE" term="%22Tomography%22">Tomography</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnosis%22">Diagnosis</searchLink>
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  Label: Geographic Terms
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22China%22">China</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Conclusions: It is impossible to make a diagnosis of temporal giant cell granuloma (GCG) before operation because of nonspecific clinical and imaging feature. Surgery is the first-line choice of treatment. Objective: To evaluate the diagnosis and treatment of temporal GCG. Methods: Eight patients with GCG receiving treatment in the Chinese PLA General Hospital between 2001 and 2010 were recruited for the study. These patients' clinical features, imaging and histopathological findings, types of surgery, and results of follow-up evaluations were noted. Results: The group was made up of four males and four females, with a median age of 37 years (range 21-50 years). Four patients had a granuloma on the left side and four on the right of the head. The median duration of the disease was 21 months (range 5-60 months). All patients, except one referred to us for recurring disease, were managed in our hospital. The main symptoms were: hearing loss ( n = 5), tinnitus ( n = 4), otalgia ( n = 3), dizziness ( n = 2), and local masses ( n = 2). Radiological examination of the masses revealed erosion of the temporal bone and base of the skull. There was no definitive diagnosis in any of the patients before surgery. All patients had surgical treatment, six of them by middle cranial fossa approach and two by combined cranio-auricular approach. Surgical complications included partial facial paralysis (three cases) and cerebral edema (one case) but they resolved soon after surgery. One patient was lost to follow-up, but the other seven were followed up over a mean period of 24 months; none has reported a recurrence. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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    Identifiers:
      – Type: doi
        Value: 10.3109/00016489.2012.654853
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 6
        StartPage: 657
    Subjects:
      – SubjectFull: Temporal bone surgery
        Type: general
      – SubjectFull: Audiometry
        Type: general
      – SubjectFull: Digital subtraction angiography
        Type: general
      – SubjectFull: Earache
        Type: general
      – SubjectFull: Giant cell tumors
        Type: general
      – SubjectFull: Granuloma
        Type: general
      – SubjectFull: Hearing disorders
        Type: general
      – SubjectFull: Magnetic resonance imaging
        Type: general
      – SubjectFull: Otoscopy
        Type: general
      – SubjectFull: Operative surgery
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      – SubjectFull: Tinnitus
        Type: general
      – SubjectFull: Tomography
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      – SubjectFull: Descriptive statistics
        Type: general
      – SubjectFull: Diagnosis
        Type: general
      – SubjectFull: China
        Type: general
    Titles:
      – TitleFull: Diagnosis and treatment of giant cell granuloma of the temporal bone: Report of eight cases.
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              M: 06
              Text: Jun2012
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