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Drug-related cues exacerbate decision making and increase craving in heroin addicts at different abstinence times.

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Title: Drug-related cues exacerbate decision making and increase craving in heroin addicts at different abstinence times.
Authors: Wang, Gui-Bin, Zhang, Xiao-Li, Zhao, Li-Yan, Sun, Li-Li, Wu, Ping, Lu, Lin, Shi, Jie
Source: Psychopharmacology. Jun2012, Vol. 221 Issue 4, p701-708. 8p.
Subjects: Decision making, People with heroin addiction, Blood pressure measurement, Temperance, Drug abuse, Heart beat
Abstract: Rationale: Relapse is a persistent problem in the management of addiction. Drug-related cues are powerful instigators of relapse. Impulsive decision making may contribute to relapse through a poorly considered assessment of the consequences of drug use. Drug cues robustly increase subjective craving, which is frequently associated with relapse. Objective: The present study explored the effects of drug-related cues on decision making and craving in heroin addicts at different abstinence times: 1, 3, 12, and 24 months. Methods: The 75 male participants were given 5 min exposure to neutral and drug-associated cues while decision making performance, craving, blood pressure, heart rate, and emotional state pre- and post-exposure were assessed. The Iowa Gambling Task was used to evaluate decision making ability in heroin addicts. Results: Drug-related cues exacerbated impulsive decision making and increased craving, heart rate, and systolic pressure in heroin addicts at all abstinence times. Conclusions: Drug-related cues aggravated decision making and increased craving in former heroin addicts who had been drug-free for 1-24 months, which might have significant clinical implications for the prevention of relapse. [ABSTRACT FROM AUTHOR]
Copyright of Psychopharmacology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Drug-related cues exacerbate decision making and increase craving in heroin addicts at different abstinence times.
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  Data: <searchLink fieldCode="AR" term="%22Wang%2C+Gui-Bin%22">Wang, Gui-Bin</searchLink><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Xiao-Li%22">Zhang, Xiao-Li</searchLink><br /><searchLink fieldCode="AR" term="%22Zhao%2C+Li-Yan%22">Zhao, Li-Yan</searchLink><br /><searchLink fieldCode="AR" term="%22Sun%2C+Li-Li%22">Sun, Li-Li</searchLink><br /><searchLink fieldCode="AR" term="%22Wu%2C+Ping%22">Wu, Ping</searchLink><br /><searchLink fieldCode="AR" term="%22Lu%2C+Lin%22">Lu, Lin</searchLink><br /><searchLink fieldCode="AR" term="%22Shi%2C+Jie%22">Shi, Jie</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Psychopharmacology%22">Psychopharmacology</searchLink>. Jun2012, Vol. 221 Issue 4, p701-708. 8p.
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  Data: <searchLink fieldCode="DE" term="%22Decision+making%22">Decision making</searchLink><br /><searchLink fieldCode="DE" term="%22People+with+heroin+addiction%22">People with heroin addiction</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+pressure+measurement%22">Blood pressure measurement</searchLink><br /><searchLink fieldCode="DE" term="%22Temperance%22">Temperance</searchLink><br /><searchLink fieldCode="DE" term="%22Drug+abuse%22">Drug abuse</searchLink><br /><searchLink fieldCode="DE" term="%22Heart+beat%22">Heart beat</searchLink>
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  Label: Abstract
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  Data: Rationale: Relapse is a persistent problem in the management of addiction. Drug-related cues are powerful instigators of relapse. Impulsive decision making may contribute to relapse through a poorly considered assessment of the consequences of drug use. Drug cues robustly increase subjective craving, which is frequently associated with relapse. Objective: The present study explored the effects of drug-related cues on decision making and craving in heroin addicts at different abstinence times: 1, 3, 12, and 24 months. Methods: The 75 male participants were given 5 min exposure to neutral and drug-associated cues while decision making performance, craving, blood pressure, heart rate, and emotional state pre- and post-exposure were assessed. The Iowa Gambling Task was used to evaluate decision making ability in heroin addicts. Results: Drug-related cues exacerbated impulsive decision making and increased craving, heart rate, and systolic pressure in heroin addicts at all abstinence times. Conclusions: Drug-related cues aggravated decision making and increased craving in former heroin addicts who had been drug-free for 1-24 months, which might have significant clinical implications for the prevention of relapse. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Psychopharmacology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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