Bibliographic Details
| Title: |
Host-Gut Microbiota Metabolic Interactions. |
| Authors: |
Nicholson, Jeremy K., Holmes, Elaine, Kinross, James, Burcelin, Remy, Gibson, Glenn, Wei Jia, Petterssons, Sven |
| Source: |
Science (pre-March 2025). 6/8/2012, Vol. 336 Issue 6086, p1262-1267. 6p. |
| Subjects: |
Gut microbiota, Microbial metabolism, Coevolution, Cellular signal transduction, Immune system, Inflammation, Liver physiology, Muscle physiology, Brain physiology, Physiology |
| Abstract: |
The composition and activity of the gut microbiota codevelop with the host from birth and is subject to a complex interplay that depends on the host genome, nutrition, and life-style. The gut microbiota is involved in the regulation of multiple host metabolic pathways, giving rise to interactive host-microbiota metabolic, signaling, and immune-inflammatory axes that physiologically connect the gut, liver, muscle, and brain. A deeper understanding of these axes is a prerequisite for optimizing therapeutic strategies to manipulate the gut microbiota to combat disease and improve health. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
