Bibliographic Details
| Title: |
Successful treatment of a woman with relapsing neuromyelitis optica by interferon beta. |
| Authors: |
Xu, Yan, Zhang, Yao, Ye, Jing, Peng, Bin, Wang, Jian-Ming, Cui, Li-Ying |
| Source: |
Neurological Sciences. Aug2012, Vol. 33 Issue 4, p911-913. 3p. |
| Subjects: |
Autoimmune diseases in women, Autoimmune disease treatment, Antigens, Interferons, Disease relapse prevention, Preventive medicine, Myelin oligodendrocyte glycoprotein, Drug efficacy |
| Abstract: |
Neuromyelitis optica (NMO) is an antibody-mediated disease with the target antigen being the water channel aquaporin-4 (AQP4). More than 90% of NMO patients have relapse. Optimal treatments to prevent recurrence have not been established. Previous reports suggest that interferon beta (IFNB) has not been effective in NMO. However, we present a case of NMO with positive anti-myelin oligodendrocyte glycoprotein (MOG) IgG and anti-AQP4 IgG treated with IFNB-1a successfully. The effect of IFNB on NMO and the role of anti-MOG antibodies in NMO deserve further study. [ABSTRACT FROM AUTHOR] |
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| Database: |
Psychology and Behavioral Sciences Collection |
