Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease.
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| Title: | Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. |
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| Authors: | Qureshi, Irfan A., Mehler, Mark F. |
| Source: | Nature Reviews Neuroscience. Aug2012, Vol. 13 Issue 8, p528-541. 14p. 4 Diagrams, 2 Charts. |
| Subjects: | Non-coding RNA, Neural development, Physiological adaptation, Neuroplasticity, Eukaryotic genomes, Tumor proteins, Genetics |
| Abstract: | Novel classes of small and long non-coding RNAs (ncRNAs) are being characterized at a rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture, regulation and transcriptional output, as well as by innovations in sequencing technologies and computational and systems biology. These ncRNAs can interact with DNA, RNA and protein molecules; engage in diverse structural, functional and regulatory activities; and have roles in nuclear organization and transcriptional, post-transcriptional and epigenetic processes. This expanding inventory of ncRNAs is implicated in mediating a broad spectrum of processes including brain evolution, development, synaptic plasticity and disease pathogenesis. [ABSTRACT FROM AUTHOR] |
| Copyright of Nature Reviews Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 77907816 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Qureshi%2C+Irfan+A%2E%22">Qureshi, Irfan A.</searchLink><br /><searchLink fieldCode="AR" term="%22Mehler%2C+Mark+F%2E%22">Mehler, Mark F.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Nature+Reviews+Neuroscience%22">Nature Reviews Neuroscience</searchLink>. Aug2012, Vol. 13 Issue 8, p528-541. 14p. 4 Diagrams, 2 Charts. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Non-coding+RNA%22">Non-coding RNA</searchLink><br /><searchLink fieldCode="DE" term="%22Neural+development%22">Neural development</searchLink><br /><searchLink fieldCode="DE" term="%22Physiological+adaptation%22">Physiological adaptation</searchLink><br /><searchLink fieldCode="DE" term="%22Neuroplasticity%22">Neuroplasticity</searchLink><br /><searchLink fieldCode="DE" term="%22Eukaryotic+genomes%22">Eukaryotic genomes</searchLink><br /><searchLink fieldCode="DE" term="%22Tumor+proteins%22">Tumor proteins</searchLink><br /><searchLink fieldCode="DE" term="%22Genetics%22">Genetics</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Novel classes of small and long non-coding RNAs (ncRNAs) are being characterized at a rapid pace, driven by recent paradigm shifts in our understanding of genomic architecture, regulation and transcriptional output, as well as by innovations in sequencing technologies and computational and systems biology. These ncRNAs can interact with DNA, RNA and protein molecules; engage in diverse structural, functional and regulatory activities; and have roles in nuclear organization and transcriptional, post-transcriptional and epigenetic processes. This expanding inventory of ncRNAs is implicated in mediating a broad spectrum of processes including brain evolution, development, synaptic plasticity and disease pathogenesis. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Nature Reviews Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=77907816 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/nrn3234 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 14 StartPage: 528 Subjects: – SubjectFull: Non-coding RNA Type: general – SubjectFull: Neural development Type: general – SubjectFull: Physiological adaptation Type: general – SubjectFull: Neuroplasticity Type: general – SubjectFull: Eukaryotic genomes Type: general – SubjectFull: Tumor proteins Type: general – SubjectFull: Genetics Type: general Titles: – TitleFull: Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Qureshi, Irfan A. – PersonEntity: Name: NameFull: Mehler, Mark F. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: Aug2012 Type: published Y: 2012 Identifiers: – Type: issn-print Value: 1471003X Numbering: – Type: volume Value: 13 – Type: issue Value: 8 Titles: – TitleFull: Nature Reviews Neuroscience Type: main |
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