View in EDS PDF Full Text

Reliability of adverse symptom event reporting by clinicians.

Saved in:
Bibliographic Details
Title: Reliability of adverse symptom event reporting by clinicians.
Authors: Atkinson, Thomas, Li, Yuelin, Coffey, Charles, Sit, Laura, Shaw, Mary, Lavene, Dawn, Bennett, Antonia, Fruscione, Mike, Rogak, Lauren, Hay, Jennifer, Gönen, Mithat, Schrag, Deborah, Basch, Ethan
Source: Quality of Life Research. Sep2012, Vol. 21 Issue 7, p1159-1164. 6p. 2 Charts, 1 Graph.
Subjects: Drug toxicity, Reliability (Personality trait), Symptoms, Adverse health care events, Risk assessment, Data analysis, Retrospective studies
Abstract: Purpose: Adverse symptom event reporting is vital as part of clinical trials and drug labeling to ensure patient safety and inform risk-benefit decision making. The purpose of this study was to assess the reliability of adverse event reporting of different clinicians for the same patient for the same visit. Methods: A retrospective reliability analysis was completed for a sample of 393 cancer patients (42.8% men; age 26-91, M = 62.39) from lung ( n = 134), prostate ( n = 113), and Ob/Gyn ( n = 146) clinics. These patients were each seen by two clinicians who independently rated seven Common Terminology Criteria for Adverse Events (CTCAE) symptoms. Twenty-three percent of patients were enrolled in therapeutic clinical trials. Results: The average time between rater evaluations was 68 min. Intraclass correlation coefficients were moderate for constipation (0.50), diarrhea (0.58), dyspnea (0.69), fatigue (0.50), nausea (0.52), neuropathy (0.71), and vomiting (0.46). These values demonstrated stability over follow-up visits. Two-point differences, which would likely affect treatment decisions, were most frequently seen among symptomatic patients for constipation (18%), vomiting (15%), and nausea (8%). Conclusion: Agreement between different clinicians when reporting adverse symptom events is moderate at best. Modification of approaches to adverse symptom reporting, such as patient self-reporting, should be considered. [ABSTRACT FROM AUTHOR]
Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 79340571
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Reliability of adverse symptom event reporting by clinicians.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Atkinson%2C+Thomas%22">Atkinson, Thomas</searchLink><br /><searchLink fieldCode="AR" term="%22Li%2C+Yuelin%22">Li, Yuelin</searchLink><br /><searchLink fieldCode="AR" term="%22Coffey%2C+Charles%22">Coffey, Charles</searchLink><br /><searchLink fieldCode="AR" term="%22Sit%2C+Laura%22">Sit, Laura</searchLink><br /><searchLink fieldCode="AR" term="%22Shaw%2C+Mary%22">Shaw, Mary</searchLink><br /><searchLink fieldCode="AR" term="%22Lavene%2C+Dawn%22">Lavene, Dawn</searchLink><br /><searchLink fieldCode="AR" term="%22Bennett%2C+Antonia%22">Bennett, Antonia</searchLink><br /><searchLink fieldCode="AR" term="%22Fruscione%2C+Mike%22">Fruscione, Mike</searchLink><br /><searchLink fieldCode="AR" term="%22Rogak%2C+Lauren%22">Rogak, Lauren</searchLink><br /><searchLink fieldCode="AR" term="%22Hay%2C+Jennifer%22">Hay, Jennifer</searchLink><br /><searchLink fieldCode="AR" term="%22Gönen%2C+Mithat%22">Gönen, Mithat</searchLink><br /><searchLink fieldCode="AR" term="%22Schrag%2C+Deborah%22">Schrag, Deborah</searchLink><br /><searchLink fieldCode="AR" term="%22Basch%2C+Ethan%22">Basch, Ethan</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Quality+of+Life+Research%22">Quality of Life Research</searchLink>. Sep2012, Vol. 21 Issue 7, p1159-1164. 6p. 2 Charts, 1 Graph.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Drug+toxicity%22">Drug toxicity</searchLink><br /><searchLink fieldCode="DE" term="%22Reliability+%28Personality+trait%29%22">Reliability (Personality trait)</searchLink><br /><searchLink fieldCode="DE" term="%22Symptoms%22">Symptoms</searchLink><br /><searchLink fieldCode="DE" term="%22Adverse+health+care+events%22">Adverse health care events</searchLink><br /><searchLink fieldCode="DE" term="%22Risk+assessment%22">Risk assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis%22">Data analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Retrospective+studies%22">Retrospective studies</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Purpose: Adverse symptom event reporting is vital as part of clinical trials and drug labeling to ensure patient safety and inform risk-benefit decision making. The purpose of this study was to assess the reliability of adverse event reporting of different clinicians for the same patient for the same visit. Methods: A retrospective reliability analysis was completed for a sample of 393 cancer patients (42.8% men; age 26-91, M = 62.39) from lung ( n = 134), prostate ( n = 113), and Ob/Gyn ( n = 146) clinics. These patients were each seen by two clinicians who independently rated seven Common Terminology Criteria for Adverse Events (CTCAE) symptoms. Twenty-three percent of patients were enrolled in therapeutic clinical trials. Results: The average time between rater evaluations was 68 min. Intraclass correlation coefficients were moderate for constipation (0.50), diarrhea (0.58), dyspnea (0.69), fatigue (0.50), nausea (0.52), neuropathy (0.71), and vomiting (0.46). These values demonstrated stability over follow-up visits. Two-point differences, which would likely affect treatment decisions, were most frequently seen among symptomatic patients for constipation (18%), vomiting (15%), and nausea (8%). Conclusion: Agreement between different clinicians when reporting adverse symptom events is moderate at best. Modification of approaches to adverse symptom reporting, such as patient self-reporting, should be considered. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Quality of Life Research is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=79340571
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s11136-011-0031-4
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 6
        StartPage: 1159
    Subjects:
      – SubjectFull: Drug toxicity
        Type: general
      – SubjectFull: Reliability (Personality trait)
        Type: general
      – SubjectFull: Symptoms
        Type: general
      – SubjectFull: Adverse health care events
        Type: general
      – SubjectFull: Risk assessment
        Type: general
      – SubjectFull: Data analysis
        Type: general
      – SubjectFull: Retrospective studies
        Type: general
    Titles:
      – TitleFull: Reliability of adverse symptom event reporting by clinicians.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Atkinson, Thomas
      – PersonEntity:
          Name:
            NameFull: Li, Yuelin
      – PersonEntity:
          Name:
            NameFull: Coffey, Charles
      – PersonEntity:
          Name:
            NameFull: Sit, Laura
      – PersonEntity:
          Name:
            NameFull: Shaw, Mary
      – PersonEntity:
          Name:
            NameFull: Lavene, Dawn
      – PersonEntity:
          Name:
            NameFull: Bennett, Antonia
      – PersonEntity:
          Name:
            NameFull: Fruscione, Mike
      – PersonEntity:
          Name:
            NameFull: Rogak, Lauren
      – PersonEntity:
          Name:
            NameFull: Hay, Jennifer
      – PersonEntity:
          Name:
            NameFull: Gönen, Mithat
      – PersonEntity:
          Name:
            NameFull: Schrag, Deborah
      – PersonEntity:
          Name:
            NameFull: Basch, Ethan
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: Sep2012
              Type: published
              Y: 2012
          Identifiers:
            – Type: issn-print
              Value: 09629343
          Numbering:
            – Type: volume
              Value: 21
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Quality of Life Research
              Type: main
ResultId 1