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Intravenous thrombolysis in ischemic stroke patients with isolated homonymous hemianopia.

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Title: Intravenous thrombolysis in ischemic stroke patients with isolated homonymous hemianopia.
Authors: Strbian, D., Soinne, L., Sairanen, T., Scheperjans, F., Salonen, O., Palomäki, M., Kaste, M., Tatlisumak, T.
Source: Acta Neurologica Scandinavica. Oct2012, Vol. 126 Issue 4, pe17-e19. 3p. 1 Black and White Photograph.
Subjects: Thrombolytic therapy, Visual fields, Brain tomography, Neuropsychological tests, Treatment effectiveness, Ischemia, Intravenous therapy, Stroke treatment, Women patients
Abstract: Background Patients with posterior ischemic stroke were usually excluded from thrombolytic treatment in clinical trials and clinical practice, and little is known about effectiveness of thrombolysis treatment in such patients who may end up with severe disability. Aims of the study We aimed to describe the outcome of acute ischemic stroke patients presenting with isolated homonymous hemianopia and treated with intravenous thrombolysis. Methods A case report of three patients presenting with homonymous hemianopia owing to posterior circulation stroke treated with intravenous thrombolysis at the Helsinki University Central Hospital. Main outcome measures were modified Rankin Scale and neuropsychological examination at 3 months after thrombolysis. We further evaluated Goldmann visual field examination at 6 months. Results No acute findings appeared on admission non-contrast head-computed tomography scan. All patients had a perfusion deficit on admission-computed tomography perfusion imaging. All patients scored 0 on 3-month modified Rankin Scale, and their neuropsychological evaluation was normal. Goldmann examination revealed no visual field deficit in both female patients, and a modest visual field defect was detected in the male patient. Conclusions Our experience encourages application of intravenous thrombolytic treatment (especially when supported with multimodality neuroimaging) in patients with homonymous hemianopia, for which rehabilitation options are limited. [ABSTRACT FROM AUTHOR]
Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Intravenous thrombolysis in ischemic stroke patients with isolated homonymous hemianopia.
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  Data: <searchLink fieldCode="AR" term="%22Strbian%2C+D%2E%22">Strbian, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Soinne%2C+L%2E%22">Soinne, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Sairanen%2C+T%2E%22">Sairanen, T.</searchLink><br /><searchLink fieldCode="AR" term="%22Scheperjans%2C+F%2E%22">Scheperjans, F.</searchLink><br /><searchLink fieldCode="AR" term="%22Salonen%2C+O%2E%22">Salonen, O.</searchLink><br /><searchLink fieldCode="AR" term="%22Palomäki%2C+M%2E%22">Palomäki, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Kaste%2C+M%2E%22">Kaste, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Tatlisumak%2C+T%2E%22">Tatlisumak, T.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Acta+Neurologica+Scandinavica%22">Acta Neurologica Scandinavica</searchLink>. Oct2012, Vol. 126 Issue 4, pe17-e19. 3p. 1 Black and White Photograph.
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  Data: <searchLink fieldCode="DE" term="%22Thrombolytic+therapy%22">Thrombolytic therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Visual+fields%22">Visual fields</searchLink><br /><searchLink fieldCode="DE" term="%22Brain+tomography%22">Brain tomography</searchLink><br /><searchLink fieldCode="DE" term="%22Neuropsychological+tests%22">Neuropsychological tests</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Ischemia%22">Ischemia</searchLink><br /><searchLink fieldCode="DE" term="%22Intravenous+therapy%22">Intravenous therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Stroke+treatment%22">Stroke treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Women+patients%22">Women patients</searchLink>
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  Data: Background Patients with posterior ischemic stroke were usually excluded from thrombolytic treatment in clinical trials and clinical practice, and little is known about effectiveness of thrombolysis treatment in such patients who may end up with severe disability. Aims of the study We aimed to describe the outcome of acute ischemic stroke patients presenting with isolated homonymous hemianopia and treated with intravenous thrombolysis. Methods A case report of three patients presenting with homonymous hemianopia owing to posterior circulation stroke treated with intravenous thrombolysis at the Helsinki University Central Hospital. Main outcome measures were modified Rankin Scale and neuropsychological examination at 3 months after thrombolysis. We further evaluated Goldmann visual field examination at 6 months. Results No acute findings appeared on admission non-contrast head-computed tomography scan. All patients had a perfusion deficit on admission-computed tomography perfusion imaging. All patients scored 0 on 3-month modified Rankin Scale, and their neuropsychological evaluation was normal. Goldmann examination revealed no visual field deficit in both female patients, and a modest visual field defect was detected in the male patient. Conclusions Our experience encourages application of intravenous thrombolytic treatment (especially when supported with multimodality neuroimaging) in patients with homonymous hemianopia, for which rehabilitation options are limited. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1111/j.1600-0404.2012.01646.x
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              Text: Oct2012
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