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Psychopathological long-term outcome of schizophrenia - a review.

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Title: Psychopathological long-term outcome of schizophrenia - a review.
Authors: Lang, F. U., Kösters, M., Lang, S., Becker, T., Jäger, M.
Source: Acta Psychiatrica Scandinavica. Mar2013, Vol. 127 Issue 3, p173-182. 10p. 1 Diagram, 4 Charts.
Subjects: Diagnosis of schizophrenia, Pathological psychology, Schizoaffective disorders, Mental health, Psychiatric research
Abstract: Objective In the past, the comparability of empirical studies that examined the course and outcome of schizophrenia was limited by their use of different diagnostic systems. Focussing on the psychopathological long-term outcome, the present article aims to review follow-up studies that used modern operationalized diagnostic criteria for schizophrenia ( DSM- III, DSM- III-R, DSM- IV and ICD-10). Method We searched MEDLINE, the Cochrane Central Register of Controlled Trials, EMBASE, Psyc INFO and PSYNDEX for relevant studies up to the year 2011. Twenty-one studies were included in the final analysis. Results The long-term outcome of schizophrenia was heterogeneous and included full remissions as well as severe chronic states. Schizophrenia, however, showed a considerably more unfavourable outcome than other diagnostic groups such as schizoaffective or affective disorders. Psychopathological symptoms remained relatively stable in the course of illness. Several predictors for a poor outcome were identified, such as male gender or pronounced negative symptoms. Conclusion Recent studies using modern diagnostic systems largely confirm the results of earlier studies. Current diagnostic criteria for schizophrenia identify a heterogeneous sample of patients. The influence of therapeutic interventions on long-term outcome remains unclear. [ABSTRACT FROM AUTHOR]
Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Psychopathological long-term outcome of schizophrenia - a review.
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  Data: <searchLink fieldCode="AR" term="%22Lang%2C+F%2E+U%2E%22">Lang, F. U.</searchLink><br /><searchLink fieldCode="AR" term="%22Kösters%2C+M%2E%22">Kösters, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Lang%2C+S%2E%22">Lang, S.</searchLink><br /><searchLink fieldCode="AR" term="%22Becker%2C+T%2E%22">Becker, T.</searchLink><br /><searchLink fieldCode="AR" term="%22Jäger%2C+M%2E%22">Jäger, M.</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22Acta+Psychiatrica+Scandinavica%22">Acta Psychiatrica Scandinavica</searchLink>. Mar2013, Vol. 127 Issue 3, p173-182. 10p. 1 Diagram, 4 Charts.
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  Data: <searchLink fieldCode="DE" term="%22Diagnosis+of+schizophrenia%22">Diagnosis of schizophrenia</searchLink><br /><searchLink fieldCode="DE" term="%22Pathological+psychology%22">Pathological psychology</searchLink><br /><searchLink fieldCode="DE" term="%22Schizoaffective+disorders%22">Schizoaffective disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+health%22">Mental health</searchLink><br /><searchLink fieldCode="DE" term="%22Psychiatric+research%22">Psychiatric research</searchLink>
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  Data: Objective In the past, the comparability of empirical studies that examined the course and outcome of schizophrenia was limited by their use of different diagnostic systems. Focussing on the psychopathological long-term outcome, the present article aims to review follow-up studies that used modern operationalized diagnostic criteria for schizophrenia ( DSM- III, DSM- III-R, DSM- IV and ICD-10). Method We searched MEDLINE, the Cochrane Central Register of Controlled Trials, EMBASE, Psyc INFO and PSYNDEX for relevant studies up to the year 2011. Twenty-one studies were included in the final analysis. Results The long-term outcome of schizophrenia was heterogeneous and included full remissions as well as severe chronic states. Schizophrenia, however, showed a considerably more unfavourable outcome than other diagnostic groups such as schizoaffective or affective disorders. Psychopathological symptoms remained relatively stable in the course of illness. Several predictors for a poor outcome were identified, such as male gender or pronounced negative symptoms. Conclusion Recent studies using modern diagnostic systems largely confirm the results of earlier studies. Current diagnostic criteria for schizophrenia identify a heterogeneous sample of patients. The influence of therapeutic interventions on long-term outcome remains unclear. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Acta Psychiatrica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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