Cortical thickness of superior frontal cortex predicts impulsiveness and perceptual reasoning in adolescence.
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| Title: | Cortical thickness of superior frontal cortex predicts impulsiveness and perceptual reasoning in adolescence. |
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| Authors: | Schilling, C, Kühn, S, Paus, T, Romanowski, A, Banaschewski, T, Barbot, A, Barker, G J, Brühl, R, Büchel, C, Conrod, P J, Dalley, J W, Flor, H, Ittermann, B, Ivanov, N, Mann, K, Martinot, J-L, Nees, F, Rietschel, M, Robbins, T W, Smolka, M N |
| Source: | Molecular Psychiatry. May2013, Vol. 18 Issue 5, p624-630. 7p. 1 Black and White Photograph, 1 Chart, 2 Graphs. |
| Subjects: | Impulsive personality, Cognitive ability, Personality & intelligence, Prefrontal cortex, Mental illness |
| Abstract: | Impulsiveness is a pivotal personality trait representing a core domain in all major personality inventories. Recently, impulsiveness has been identified as an important modulator of cognitive processing, particularly in tasks that require the processing of large amounts of information. Although brain imaging studies have implicated the prefrontal cortex to be a common underlying representation of impulsiveness and related cognitive functioning, to date a fine-grain and detailed morphometric analysis has not been carried out. On the basis of ahigh-resolution magnetic resonance scans acquired in 1620 healthy adolescents (IMAGEN), the individual cortical thickness (CT) was estimated. Correlations between Cloninger's impulsiveness and CT were studied in an entire cortex analysis. The cluster identified was tested for associations with performance in perceptual reasoning tasks of the Wechsler Intelligence Scale for Children (WISC IV). We observed a significant inverse correlation between trait impulsiveness and CT of the left superior frontal cortex (SFC; Monte Carlo Simulation P<0.01). CT within this cluster correlated with perceptual reasoning scores (Bonferroni corrected) of the WISC IV. On the basis of a large sample of adolescents, we identified an extended area in the SFC as a correlate of impulsiveness, which appears to be in line with the trait character of this prominent personality facet. The association of SFC thickness with perceptual reasoning argues for a common neurobiological basis of personality and specific cognitive domains comprising attention, spatial reasoning and response selection. The results may facilitate the understanding of the role of impulsiveness in several psychiatric disorders associated with prefrontal dysfunctions and cognitive deficits. [ABSTRACT FROM AUTHOR] |
| Copyright of Molecular Psychiatry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 87085765 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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May2013, Vol. 18 Issue 5, p624-630. 7p. 1 Black and White Photograph, 1 Chart, 2 Graphs. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Impulsive+personality%22">Impulsive personality</searchLink><br /><searchLink fieldCode="DE" term="%22Cognitive+ability%22">Cognitive ability</searchLink><br /><searchLink fieldCode="DE" term="%22Personality+%26+intelligence%22">Personality & intelligence</searchLink><br /><searchLink fieldCode="DE" term="%22Prefrontal+cortex%22">Prefrontal cortex</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+illness%22">Mental illness</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Impulsiveness is a pivotal personality trait representing a core domain in all major personality inventories. Recently, impulsiveness has been identified as an important modulator of cognitive processing, particularly in tasks that require the processing of large amounts of information. 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On the basis of a large sample of adolescents, we identified an extended area in the SFC as a correlate of impulsiveness, which appears to be in line with the trait character of this prominent personality facet. The association of SFC thickness with perceptual reasoning argues for a common neurobiological basis of personality and specific cognitive domains comprising attention, spatial reasoning and response selection. The results may facilitate the understanding of the role of impulsiveness in several psychiatric disorders associated with prefrontal dysfunctions and cognitive deficits. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Molecular Psychiatry is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/mp.2012.56 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 624 Subjects: – SubjectFull: Impulsive personality Type: general – SubjectFull: Cognitive ability Type: general – SubjectFull: Personality & intelligence Type: general – SubjectFull: Prefrontal cortex Type: general – SubjectFull: Mental illness Type: general Titles: – TitleFull: Cortical thickness of superior frontal cortex predicts impulsiveness and perceptual reasoning in adolescence. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Schilling, C – PersonEntity: Name: NameFull: Kühn, S – PersonEntity: Name: NameFull: Paus, T – PersonEntity: Name: NameFull: Romanowski, A – PersonEntity: Name: NameFull: Banaschewski, T – PersonEntity: Name: NameFull: Barbot, A – PersonEntity: Name: NameFull: Barker, G J – PersonEntity: Name: NameFull: Brühl, R – PersonEntity: Name: NameFull: Büchel, C – PersonEntity: Name: NameFull: Conrod, P J – PersonEntity: Name: NameFull: Dalley, J W – PersonEntity: Name: NameFull: Flor, H – PersonEntity: Name: NameFull: Ittermann, B – PersonEntity: Name: NameFull: Ivanov, N – PersonEntity: Name: NameFull: Mann, K – PersonEntity: Name: NameFull: Martinot, J-L – PersonEntity: Name: NameFull: Nees, F – PersonEntity: Name: NameFull: Rietschel, M – PersonEntity: Name: NameFull: Robbins, T W – PersonEntity: Name: NameFull: Smolka, M N IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2013 Type: published Y: 2013 Identifiers: – Type: issn-print Value: 13594184 Numbering: – Type: volume Value: 18 – Type: issue Value: 5 Titles: – TitleFull: Molecular Psychiatry Type: main |
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