Pain-related neurons in the human cingulate cortex.

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Bibliographic Details
Title: Pain-related neurons in the human cingulate cortex.
Authors: Hutchison, W. D., Davis, K. D., Lozano, A. M., Tasker, R. R., Dostrovsky, J. O.
Source: Nature Neuroscience. May99, Vol. 2 Issue 5, p403. 3p.
Subjects: Neurons, Pain, Sensory perception
Abstract: Although it is widely accepted that the cortex participates in pain perception, there is no direct evidence for the existence of cortical neurons that respond to noxious or painful stimuli in humans. Anatomical and neurophysiological studies in animals as well as brain imaging and evoked potential studies in humans suggest that the anterior cingulate cortex (ACC) is an important area for processing sensory information related to pain. We have now identified single neurons in ACC that respond selectively to painful thermal and mechanical stimuli, supporting a role for the ACC in pain perception. [ABSTRACT FROM AUTHOR]
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Database: Psychology and Behavioral Sciences Collection
Description
Abstract:Although it is widely accepted that the cortex participates in pain perception, there is no direct evidence for the existence of cortical neurons that respond to noxious or painful stimuli in humans. Anatomical and neurophysiological studies in animals as well as brain imaging and evoked potential studies in humans suggest that the anterior cingulate cortex (ACC) is an important area for processing sensory information related to pain. We have now identified single neurons in ACC that respond selectively to painful thermal and mechanical stimuli, supporting a role for the ACC in pain perception. [ABSTRACT FROM AUTHOR]
ISSN:10976256
DOI:10.1038/8065