Young adult ischaemic stroke related acute symptomatic and late seizures: risk factors.
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| Title: | Young adult ischaemic stroke related acute symptomatic and late seizures: risk factors. |
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| Authors: | Roivainen, R., Haapaniemi, E., Putaala, J., Kaste, M., Tatlisumak, T. |
| Source: | European Journal of Neurology. Sep2013, Vol. 20 Issue 9, p1247-1255. 9p. 1 Diagram, 3 Charts, 1 Graph. |
| Subjects: | Risk factors of spasms, Stroke patients, Helsinki University Central Hospital (Helsinki, Finland), Proportional hazards models, National Institutes of Health (U.S.), Multivariate analysis, Longitudinal method |
| Abstract: | Background and purpose After first-ever ischaemic stroke, to assess the risk and baseline factors associated with acute symptomatic seizure ( ASS) (occurring within 7 days) and late post-stroke seizure ( LPS) (>7 days). Methods All consecutive patients aged 15-49 with first-ever ischaemic stroke between 1994 and 2007 treated at the Helsinki University Central Hospital were included, using Cox proportional hazard models to identify factors associated with seizures. Adjustment was for age, gender, vascular risk factors, admission hyperglycemia (>6.1 mm) and hyponatremia (<137 mm), use of psychiatric medication, stroke severity ( NIH Stroke Scale) and anatomical (Bamford criteria) and etiological (Trial of Org in Acute Stroke Treatment) stroke subtype. Results ASSs emerged in 35 (3.5%) patients. LPSs ( n = 102) occurred at a cumulative rate of 6.1% at 1 year, 9.5% at 5 years and 11.5% at 10 years. In multivariate analysis, anxiolytic use at time of index stroke (hazard ratio 13.43, 95% confidence interval 3.91-46.14), moderate stroke severity (3.95, 1.86-8.41), cortical involvement (3.69, 1.66-8.18) and hyponatremia (3.26, 1.41-7.57) were independently associated with ASSs. Risk factors for LPSs were total anterior circulation infarct (15.94, 7.62-33.33), partial anterior circulation infarct (3.48, 1.52-7.93), history of ASS (3.94, 2.07-7.48), antidepressant use at the time of LPS (3.88, 2.46-6.11), hemorrhagic infarct (1.94, 1.19-3.15), male gender (1.79, 1.10-2.92) and hyperglycemia (1.62, 1.05-2.51). Conclusions In young ischaemic stroke patients, the magnitude of seizure risk and the major risk factors were similar to older ischaemic stroke patients but risk factors for ASSs and LPSs differed. [ABSTRACT FROM AUTHOR] |
| Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 89411020 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Young adult ischaemic stroke related acute symptomatic and late seizures: risk factors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Roivainen%2C+R%2E%22">Roivainen, R.</searchLink><br /><searchLink fieldCode="AR" term="%22Haapaniemi%2C+E%2E%22">Haapaniemi, E.</searchLink><br /><searchLink fieldCode="AR" term="%22Putaala%2C+J%2E%22">Putaala, J.</searchLink><br /><searchLink fieldCode="AR" term="%22Kaste%2C+M%2E%22">Kaste, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Tatlisumak%2C+T%2E%22">Tatlisumak, T.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neurology%22">European Journal of Neurology</searchLink>. Sep2013, Vol. 20 Issue 9, p1247-1255. 9p. 1 Diagram, 3 Charts, 1 Graph. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Risk+factors+of+spasms%22">Risk factors of spasms</searchLink><br /><searchLink fieldCode="DE" term="%22Stroke+patients%22">Stroke patients</searchLink><br /><searchLink fieldCode="DE" term="%22Helsinki+University+Central+Hospital+%28Helsinki%2C+Finland%29%22">Helsinki University Central Hospital (Helsinki, Finland)</searchLink><br /><searchLink fieldCode="DE" term="%22Proportional+hazards+models%22">Proportional hazards models</searchLink><br /><searchLink fieldCode="DE" term="%22National+Institutes+of+Health+%28U%2ES%2E%29%22">National Institutes of Health (U.S.)</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+analysis%22">Multivariate analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Longitudinal+method%22">Longitudinal method</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Background and purpose After first-ever ischaemic stroke, to assess the risk and baseline factors associated with acute symptomatic seizure ( ASS) (occurring within 7 days) and late post-stroke seizure ( LPS) (>7 days). Methods All consecutive patients aged 15-49 with first-ever ischaemic stroke between 1994 and 2007 treated at the Helsinki University Central Hospital were included, using Cox proportional hazard models to identify factors associated with seizures. Adjustment was for age, gender, vascular risk factors, admission hyperglycemia (>6.1 mm) and hyponatremia (<137 mm), use of psychiatric medication, stroke severity ( NIH Stroke Scale) and anatomical (Bamford criteria) and etiological (Trial of Org in Acute Stroke Treatment) stroke subtype. Results ASSs emerged in 35 (3.5%) patients. LPSs ( n = 102) occurred at a cumulative rate of 6.1% at 1 year, 9.5% at 5 years and 11.5% at 10 years. In multivariate analysis, anxiolytic use at time of index stroke (hazard ratio 13.43, 95% confidence interval 3.91-46.14), moderate stroke severity (3.95, 1.86-8.41), cortical involvement (3.69, 1.66-8.18) and hyponatremia (3.26, 1.41-7.57) were independently associated with ASSs. Risk factors for LPSs were total anterior circulation infarct (15.94, 7.62-33.33), partial anterior circulation infarct (3.48, 1.52-7.93), history of ASS (3.94, 2.07-7.48), antidepressant use at the time of LPS (3.88, 2.46-6.11), hemorrhagic infarct (1.94, 1.19-3.15), male gender (1.79, 1.10-2.92) and hyperglycemia (1.62, 1.05-2.51). Conclusions In young ischaemic stroke patients, the magnitude of seizure risk and the major risk factors were similar to older ischaemic stroke patients but risk factors for ASSs and LPSs differed. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=89411020 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/ene.12157 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 1247 Subjects: – SubjectFull: Risk factors of spasms Type: general – SubjectFull: Stroke patients Type: general – SubjectFull: Helsinki University Central Hospital (Helsinki, Finland) Type: general – SubjectFull: Proportional hazards models Type: general – SubjectFull: National Institutes of Health (U.S.) Type: general – SubjectFull: Multivariate analysis Type: general – SubjectFull: Longitudinal method Type: general Titles: – TitleFull: Young adult ischaemic stroke related acute symptomatic and late seizures: risk factors. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Roivainen, R. – PersonEntity: Name: NameFull: Haapaniemi, E. – PersonEntity: Name: NameFull: Putaala, J. – PersonEntity: Name: NameFull: Kaste, M. – PersonEntity: Name: NameFull: Tatlisumak, T. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep2013 Type: published Y: 2013 Identifiers: – Type: issn-print Value: 13515101 Numbering: – Type: volume Value: 20 – Type: issue Value: 9 Titles: – TitleFull: European Journal of Neurology Type: main |
| ResultId | 1 |
