Thermosensory activation of insular cortex.
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| Title: | Thermosensory activation of insular cortex. |
|---|---|
| Authors: | Craig, A. D., Chen, K., Bandy, D., Reiman, E. M. |
| Source: | Nature Neuroscience. Feb2000, Vol. 3 Issue 2, p184. 7p. |
| Subjects: | Temperature sense, Brain, Limbic system, Pain |
| Abstract: | Temperature sensation is regarded as a submodality of touch, but evidence suggests involvement of insular cortex rather than parietal somatosensory cortices. Using positron emission tomography (PET), we found contralateral activity correlated with graded cooling stimuli only in the dorsal margin of the middle/posterior insula in humans. This corresponds to the thermoreceptive- and nociceptive-specific lamina I spinothalamocortical pathway in monkeys, and can be considered an enteroceptive area within limbic sensory cortex. Because lesions at this site can produce the poststroke central pain syndrome, this finding supports the proposal that central pain results from loss of the normal inhibition of pain by cold. Notably, perceived thermal intensity was well correlated with activation in the right (ipsilateral) anterior insular and orbitofrontal cortices. [ABSTRACT FROM AUTHOR] |
| Copyright of Nature Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 9003577 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=9003577 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/72131 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 184 Subjects: – SubjectFull: Temperature sense Type: general – SubjectFull: Brain Type: general – SubjectFull: Limbic system Type: general – SubjectFull: Pain Type: general Titles: – TitleFull: Thermosensory activation of insular cortex. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Craig, A. D. – PersonEntity: Name: NameFull: Chen, K. – PersonEntity: Name: NameFull: Bandy, D. – PersonEntity: Name: NameFull: Reiman, E. M. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2000 Type: published Y: 2000 Identifiers: – Type: issn-print Value: 10976256 Numbering: – Type: volume Value: 3 – Type: issue Value: 2 Titles: – TitleFull: Nature Neuroscience Type: main |
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