View in EDS HTML Full Text PDF Full Text

Atrial fibrillation in young stroke patients: do we underestimate its prevalence?

Saved in:
Bibliographic Details
Title: Atrial fibrillation in young stroke patients: do we underestimate its prevalence?
Authors: Prefasi, D., Martínez‐Sánchez, P., Rodríguez‐Sanz, A., Fuentes, B., Filgueiras‐Rama, D., Ruiz‐Ares, G., Sanz‐Cuesta, B. E., Díez‐Tejedor, E.
Source: European Journal of Neurology. Oct2013, Vol. 20 Issue 10, p1367-1374. 8p. 1 Diagram, 5 Charts.
Subjects: Atrial fibrillation, National Institute of Neurological Disorders & Stroke (U.S.), Etiology of diseases, Heart diseases, Atrial arrhythmias
Abstract: Background and purpose The prevalence of atrial fibrillation ( AF) in young stroke patients has rarely been reported and is considered an uncommon ischaemic stroke ( IS) aetiology. Our objective was to analyse the prevalence of AF in IS patients up to 50 years of age and its relationship with stroke severity and outcomes. Methods This was an observational study of consecutive IS patients up to 50 years of age admitted to a stroke centre during a 5-year period (2007-2011). A complete cardiology study was performed with a daily electrocardiogram and cardiac monitoring for 72 h as well as echocardiography. In cases of stroke of unknown aetiology a 24-h Holter monitoring was performed. Baseline data, previously or newly diagnosed AF, structural heart disease ( SHD) (valvulopathy/cardiomyopathy), stroke severity on admission as measured by the National Institutes of Health Stroke Scale ( NIHSS) (moderate-severe stroke if NIHSS ≥ 8) and 3-month outcomes according to the modified Rankin Scale ( mRS) (good outcome if mRS ≤ 2) were analysed. AF was classified as AF associated with SHD ( AF- SHD) and AF not associated with SHD ( AF- NSHD). Results One hundred and fifty-seven patients were included (mean age 43 years, 58.6% male). Fourteen subjects (8.9%) presented with AF, four with AF- NSHD and 10 with AF- SHD. AF was previously known in 10 patients (6.3%), two with AF- NSHD and eight with AF- SHD. A multivariate analysis showed an independent association between AF and moderate-severe IS (odds ratio 3.771, 95% CI 1.182-12.028), but AF was not an independent prognostic factor. Conclusion AF may be more common than expected in young patients with IS and is associated with increased NIHSS scores. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 90180660
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Atrial fibrillation in young stroke patients: do we underestimate its prevalence?
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Prefasi%2C+D%2E%22">Prefasi, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Martínez‐Sánchez%2C+P%2E%22">Martínez‐Sánchez, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Rodríguez‐Sanz%2C+A%2E%22">Rodríguez‐Sanz, A.</searchLink><br /><searchLink fieldCode="AR" term="%22Fuentes%2C+B%2E%22">Fuentes, B.</searchLink><br /><searchLink fieldCode="AR" term="%22Filgueiras‐Rama%2C+D%2E%22">Filgueiras‐Rama, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Ruiz‐Ares%2C+G%2E%22">Ruiz‐Ares, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Sanz‐Cuesta%2C+B%2E+E%2E%22">Sanz‐Cuesta, B. E.</searchLink><br /><searchLink fieldCode="AR" term="%22Díez‐Tejedor%2C+E%2E%22">Díez‐Tejedor, E.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22European+Journal+of+Neurology%22">European Journal of Neurology</searchLink>. Oct2013, Vol. 20 Issue 10, p1367-1374. 8p. 1 Diagram, 5 Charts.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Atrial+fibrillation%22">Atrial fibrillation</searchLink><br /><searchLink fieldCode="DE" term="%22National+Institute+of+Neurological+Disorders+%26+Stroke+%28U%2ES%2E%29%22">National Institute of Neurological Disorders & Stroke (U.S.)</searchLink><br /><searchLink fieldCode="DE" term="%22Etiology+of+diseases%22">Etiology of diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Heart+diseases%22">Heart diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Atrial+arrhythmias%22">Atrial arrhythmias</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background and purpose The prevalence of atrial fibrillation ( AF) in young stroke patients has rarely been reported and is considered an uncommon ischaemic stroke ( IS) aetiology. Our objective was to analyse the prevalence of AF in IS patients up to 50 years of age and its relationship with stroke severity and outcomes. Methods This was an observational study of consecutive IS patients up to 50 years of age admitted to a stroke centre during a 5-year period (2007-2011). A complete cardiology study was performed with a daily electrocardiogram and cardiac monitoring for 72 h as well as echocardiography. In cases of stroke of unknown aetiology a 24-h Holter monitoring was performed. Baseline data, previously or newly diagnosed AF, structural heart disease ( SHD) (valvulopathy/cardiomyopathy), stroke severity on admission as measured by the National Institutes of Health Stroke Scale ( NIHSS) (moderate-severe stroke if NIHSS ≥ 8) and 3-month outcomes according to the modified Rankin Scale ( mRS) (good outcome if mRS ≤ 2) were analysed. AF was classified as AF associated with SHD ( AF- SHD) and AF not associated with SHD ( AF- NSHD). Results One hundred and fifty-seven patients were included (mean age 43 years, 58.6% male). Fourteen subjects (8.9%) presented with AF, four with AF- NSHD and 10 with AF- SHD. AF was previously known in 10 patients (6.3%), two with AF- NSHD and eight with AF- SHD. A multivariate analysis showed an independent association between AF and moderate-severe IS (odds ratio 3.771, 95% CI 1.182-12.028), but AF was not an independent prognostic factor. Conclusion AF may be more common than expected in young patients with IS and is associated with increased NIHSS scores. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=90180660
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1111/ene.12187
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 8
        StartPage: 1367
    Subjects:
      – SubjectFull: Atrial fibrillation
        Type: general
      – SubjectFull: National Institute of Neurological Disorders & Stroke (U.S.)
        Type: general
      – SubjectFull: Etiology of diseases
        Type: general
      – SubjectFull: Heart diseases
        Type: general
      – SubjectFull: Atrial arrhythmias
        Type: general
    Titles:
      – TitleFull: Atrial fibrillation in young stroke patients: do we underestimate its prevalence?
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Prefasi, D.
      – PersonEntity:
          Name:
            NameFull: Martínez‐Sánchez, P.
      – PersonEntity:
          Name:
            NameFull: Rodríguez‐Sanz, A.
      – PersonEntity:
          Name:
            NameFull: Fuentes, B.
      – PersonEntity:
          Name:
            NameFull: Filgueiras‐Rama, D.
      – PersonEntity:
          Name:
            NameFull: Ruiz‐Ares, G.
      – PersonEntity:
          Name:
            NameFull: Sanz‐Cuesta, B. E.
      – PersonEntity:
          Name:
            NameFull: Díez‐Tejedor, E.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: Oct2013
              Type: published
              Y: 2013
          Identifiers:
            – Type: issn-print
              Value: 13515101
          Numbering:
            – Type: volume
              Value: 20
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: European Journal of Neurology
              Type: main
ResultId 1