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Greater occipital nerve blocks in chronic cluster headache: a prospective open-label study.

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Title: Greater occipital nerve blocks in chronic cluster headache: a prospective open-label study.
Authors: Lambru, G., Abu Bakar, N., Stahlhut, L., McCulloch, S., Miller, S., Shanahan, P., Matharu, M. S.
Source: European Journal of Neurology. Feb2014, Vol. 21 Issue 2, p338-343. 6p.
Subjects: National Hospital for Neurology & Neurosurgery (London, England), Cluster headache, Adrenocortical hormones, Local anesthetics, Cerebrovascular disease
Abstract: Background and purpose Greater occipital nerve blockade ( GONB) has been shown to be effective in episodic cluster headache. However, its use in chronic cluster headache ( CCH) is less certain. The study aims to prospectively assess the efficacy and consistency of response to GONB in a large series of CCH patients. Methods CCH patients who had a unilateral GONB and were referred to the National Hospital for Neurology and Neurosurgery were studied prospectively. Headache characteristics were collected using headache diaries. Responders were considered to be patients with a complete or partial response lasting at least 7 days. In a subgroup of responders the outcomes of serial GONB performed at 3-monthly intervals were also analysed. Results Eighty-three CCH patients were studied. After the first GONB, a positive response was observed in 47 (57%) patients: 35 (42%) were rendered pain free, 12 (15%) had a partial benefit and one patient obtained <50% improvement. The duration of a positive response lasted a median of 21 days (range 7-504 days). There was a transient worsening of condition in 6% of patients. The overall rate and average duration of response remained consistent after the second [ n = 37; 31 responders (84%); median duration 21 days], third [ n = 28; 20 responders (71%); median duration 25 days] and fourth [ n = 14; 10 responders (71%); median duration 23 days] injections. Conclusion GONB seems to be an efficacious treatment with reproducible effects in CCH patients. Performed three monthly, GONB may have a useful role in the management of CCH. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Greater occipital nerve blocks in chronic cluster headache: a prospective open-label study.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lambru%2C+G%2E%22&quot;&gt;Lambru, G.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Abu+Bakar%2C+N%2E%22&quot;&gt;Abu Bakar, N.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Stahlhut%2C+L%2E%22&quot;&gt;Stahlhut, L.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22McCulloch%2C+S%2E%22&quot;&gt;McCulloch, S.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Miller%2C+S%2E%22&quot;&gt;Miller, S.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Shanahan%2C+P%2E%22&quot;&gt;Shanahan, P.&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Matharu%2C+M%2E+S%2E%22&quot;&gt;Matharu, M. S.&lt;/searchLink&gt;
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Journal+of+Neurology%22&quot;&gt;European Journal of Neurology&lt;/searchLink&gt;. Feb2014, Vol. 21 Issue 2, p338-343. 6p.
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  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22National+Hospital+for+Neurology+%26+Neurosurgery+%28London%2C+England%29%22&quot;&gt;National Hospital for Neurology &amp; Neurosurgery (London, England)&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cluster+headache%22&quot;&gt;Cluster headache&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Adrenocortical+hormones%22&quot;&gt;Adrenocortical hormones&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Local+anesthetics%22&quot;&gt;Local anesthetics&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Cerebrovascular+disease%22&quot;&gt;Cerebrovascular disease&lt;/searchLink&gt;
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  Label: Abstract
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  Data: Background and purpose Greater occipital nerve blockade ( GONB) has been shown to be effective in episodic cluster headache. However, its use in chronic cluster headache ( CCH) is less certain. The study aims to prospectively assess the efficacy and consistency of response to GONB in a large series of CCH patients. Methods CCH patients who had a unilateral GONB and were referred to the National Hospital for Neurology and Neurosurgery were studied prospectively. Headache characteristics were collected using headache diaries. Responders were considered to be patients with a complete or partial response lasting at least 7 days. In a subgroup of responders the outcomes of serial GONB performed at 3-monthly intervals were also analysed. Results Eighty-three CCH patients were studied. After the first GONB, a positive response was observed in 47 (57%) patients: 35 (42%) were rendered pain free, 12 (15%) had a partial benefit and one patient obtained &lt;50% improvement. The duration of a positive response lasted a median of 21 days (range 7-504 days). There was a transient worsening of condition in 6% of patients. The overall rate and average duration of response remained consistent after the second [ n = 37; 31 responders (84%); median duration 21 days], third [ n = 28; 20 responders (71%); median duration 25 days] and fourth [ n = 14; 10 responders (71%); median duration 23 days] injections. Conclusion GONB seems to be an efficacious treatment with reproducible effects in CCH patients. Performed three monthly, GONB may have a useful role in the management of CCH. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of European Journal of Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1111/ene.12321
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        Text: English
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      – SubjectFull: National Hospital for Neurology & Neurosurgery (London, England)
        Type: general
      – SubjectFull: Cluster headache
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      – SubjectFull: Adrenocortical hormones
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      – SubjectFull: Local anesthetics
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      – TitleFull: Greater occipital nerve blocks in chronic cluster headache: a prospective open-label study.
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              Text: Feb2014
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