Comparison of the diagnostic value of 3 T MRI after intratympanic injection of GBCA, electrocochleography, and the glycerol test in patients with Meniere's disease.

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Title: Comparison of the diagnostic value of 3 T MRI after intratympanic injection of GBCA, electrocochleography, and the glycerol test in patients with Meniere's disease.
Authors: Fukuoka, Hisakuni (AUTHOR), Takumi, Yutaka (AUTHOR), Tsukada, Keita (AUTHOR), Miyagawa, Maiko (AUTHOR), Oguchi, Tomohiro (AUTHOR), Ueda, Hitoshi (AUTHOR), Kadoya, Masumi (AUTHOR), Usami, Shin-ichi (AUTHOR)
Source: Acta Oto-Laryngologica. Feb2012, Vol. 132 Issue 2, p141-145. 5p.
Subjects: Evoked response audiometry, Comparative studies, Glycerin, Magnetic resonance imaging, Ménière's disease, Research funding, Contrast media, Data analysis software, Descriptive statistics
Abstract: Conclusion. 3 T MRI after intratympanic injection of gadolinium-based contrast agent (GBCA) is more useful for the diagnosis of endolymphatic hydrops compared with the glycerol test and electrocochleography (ECoG). Objective: To investigate the relationship between 3 T MRI after intratympanic injection of GBCA, the glycerol test, and ECoG in patients with Meniere's disease (MD). Methods: A total of 20 patients with MD were evaluated. Diluted gadodiamide (a gadolinium-based contrast agent) was administered to the bilateral tympanic cavity by injection through the tympanic membrane. After 24 h, the endolymphatic hydrops was evaluated by a 3.0 T MR scanner. To investigate cochlear hydrops, the glycerol test and ECoG were carried out in all patients. Results: A positive result was observed in 11 patients (55%) in the glycerol test and in 12 patients (60%) by ECoG. The incidence of positive findings when evaluating the same patients with both the glycerol test and ECoG increased to 75%. Nineteen of 20 (95%) patients showed positive results for 3 T MRI [ABSTRACT FROM AUTHOR]
Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
  Group: Ti
  Data: Comparison of the diagnostic value of 3 T MRI after intratympanic injection of GBCA, electrocochleography, and the glycerol test in patients with Meniere's disease.
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  Data: <searchLink fieldCode="AR" term="%22Fukuoka%2C+Hisakuni%22">Fukuoka, Hisakuni</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Takumi%2C+Yutaka%22">Takumi, Yutaka</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tsukada%2C+Keita%22">Tsukada, Keita</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Miyagawa%2C+Maiko%22">Miyagawa, Maiko</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Oguchi%2C+Tomohiro%22">Oguchi, Tomohiro</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ueda%2C+Hitoshi%22">Ueda, Hitoshi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kadoya%2C+Masumi%22">Kadoya, Masumi</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Usami%2C+Shin-ichi%22">Usami, Shin-ichi</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Acta+Oto-Laryngologica%22">Acta Oto-Laryngologica</searchLink>. Feb2012, Vol. 132 Issue 2, p141-145. 5p.
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  Data: <searchLink fieldCode="DE" term="%22Evoked+response+audiometry%22">Evoked response audiometry</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Glycerin%22">Glycerin</searchLink><br /><searchLink fieldCode="DE" term="%22Magnetic+resonance+imaging%22">Magnetic resonance imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Ménière's+disease%22">Ménière's disease</searchLink><br /><searchLink fieldCode="DE" term="%22Research+funding%22">Research funding</searchLink><br /><searchLink fieldCode="DE" term="%22Contrast+media%22">Contrast media</searchLink><br /><searchLink fieldCode="DE" term="%22Data+analysis+software%22">Data analysis software</searchLink><br /><searchLink fieldCode="DE" term="%22Descriptive+statistics%22">Descriptive statistics</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Conclusion. 3 T MRI after intratympanic injection of gadolinium-based contrast agent (GBCA) is more useful for the diagnosis of endolymphatic hydrops compared with the glycerol test and electrocochleography (ECoG). Objective: To investigate the relationship between 3 T MRI after intratympanic injection of GBCA, the glycerol test, and ECoG in patients with Meniere's disease (MD). Methods: A total of 20 patients with MD were evaluated. Diluted gadodiamide (a gadolinium-based contrast agent) was administered to the bilateral tympanic cavity by injection through the tympanic membrane. After 24 h, the endolymphatic hydrops was evaluated by a 3.0 T MR scanner. To investigate cochlear hydrops, the glycerol test and ECoG were carried out in all patients. Results: A positive result was observed in 11 patients (55%) in the glycerol test and in 12 patients (60%) by ECoG. The incidence of positive findings when evaluating the same patients with both the glycerol test and ECoG increased to 75%. Nineteen of 20 (95%) patients showed positive results for 3 T MRI [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Oto-Laryngologica is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.3109/00016489.2011.635383
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        Text: English
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        Type: general
      – SubjectFull: Comparative studies
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      – SubjectFull: Glycerin
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      – SubjectFull: Magnetic resonance imaging
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      – SubjectFull: Contrast media
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      – SubjectFull: Data analysis software
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      – SubjectFull: Descriptive statistics
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      – TitleFull: Comparison of the diagnostic value of 3 T MRI after intratympanic injection of GBCA, electrocochleography, and the glycerol test in patients with Meniere's disease.
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              Text: Feb2012
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