View in EDS PDF Full Text

ATHEROPROTECTIVE EFFECTS OF HIGH-DENSITY LIPOPROTEINS.

Saved in:
Bibliographic Details
Title: ATHEROPROTECTIVE EFFECTS OF HIGH-DENSITY LIPOPROTEINS.
Authors: Assmann, Gerd, Nofer, Jerzy-Roch
Source: Annual Review of Medicine. 2003, Vol. 54 Issue 1, p321. 21p.
Subjects: High density lipoproteins, Arteriosclerosis, Lipoproteins
Abstract: Observational studies provide overwhelming evidence that a low high-density lipoprotein (HDL)–cholesterol level increases the risk of coronary events, both in healthy subjects and in patients with coronary heart disease. Based on in vitro experiments, several mechanistic explanations for the atheroprotective function of HDL have been suggested. However, few of these were verified in vivo in humans or in experiments with transgenic animals. The HDL functions currently most widely held to account for the antiatherogenic effect include participation in reverse cholesterol transport, protection against endothelial dysfunction, and inhibition of oxidative stress. This review summarizes current views on the molecular mechanism underlying these atheroprotective effects of HDL. [ABSTRACT FROM AUTHOR]
Copyright of Annual Review of Medicine is the property of Annual Reviews Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 9688337
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: ATHEROPROTECTIVE EFFECTS OF HIGH-DENSITY LIPOPROTEINS.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Assmann%2C+Gerd%22">Assmann, Gerd</searchLink><br /><searchLink fieldCode="AR" term="%22Nofer%2C+Jerzy-Roch%22">Nofer, Jerzy-Roch</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Annual+Review+of+Medicine%22">Annual Review of Medicine</searchLink>. 2003, Vol. 54 Issue 1, p321. 21p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22High+density+lipoproteins%22">High density lipoproteins</searchLink><br /><searchLink fieldCode="DE" term="%22Arteriosclerosis%22">Arteriosclerosis</searchLink><br /><searchLink fieldCode="DE" term="%22Lipoproteins%22">Lipoproteins</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Observational studies provide overwhelming evidence that a low high-density lipoprotein (HDL)–cholesterol level increases the risk of coronary events, both in healthy subjects and in patients with coronary heart disease. Based on in vitro experiments, several mechanistic explanations for the atheroprotective function of HDL have been suggested. However, few of these were verified in vivo in humans or in experiments with transgenic animals. The HDL functions currently most widely held to account for the antiatherogenic effect include participation in reverse cholesterol transport, protection against endothelial dysfunction, and inhibition of oxidative stress. This review summarizes current views on the molecular mechanism underlying these atheroprotective effects of HDL. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Annual Review of Medicine is the property of Annual Reviews Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=9688337
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1146/annurev.med.54.101601.152409
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 21
        StartPage: 321
    Subjects:
      – SubjectFull: High density lipoproteins
        Type: general
      – SubjectFull: Arteriosclerosis
        Type: general
      – SubjectFull: Lipoproteins
        Type: general
    Titles:
      – TitleFull: ATHEROPROTECTIVE EFFECTS OF HIGH-DENSITY LIPOPROTEINS.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Assmann, Gerd
      – PersonEntity:
          Name:
            NameFull: Nofer, Jerzy-Roch
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2003
              Type: published
              Y: 2003
          Identifiers:
            – Type: issn-print
              Value: 00664219
          Numbering:
            – Type: volume
              Value: 54
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Annual Review of Medicine
              Type: main
ResultId 1