Is the antidepressive effect of sleep deprivation stabilized by a three day phase advance of the sleep period?: A pilot study.
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| Title: | Is the antidepressive effect of sleep deprivation stabilized by a three day phase advance of the sleep period?: A pilot study. |
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| Authors: | Voderholzer, U., Valerius, G., Schaerer, L., Riemann, D., Giedke, H., Schwärzler, F., Berger, M., Wiegand, M. |
| Source: | European Archives of Psychiatry & Clinical Neuroscience. 2003, Vol. 253 Issue 2, p68. 5p. |
| Subjects: | Sleep deprivation, Insomnia, Sleep disorders, Mental depression, Antidepressants |
| Abstract: | Sleep deprivation (SD) induces a rapid amelioration of mood in about 60 % of depressed patients. After the next night of sleep, however, most patients experience a relapse. Previous studies demonstrated that a six day sleep-phase advance protocol prevents relapses in about 60 % of patients who responded positively to SD. We investigated whether also a three day phase advance of the sleep period might be able to maintain the antidepressant effects of SD. Twenty-eight medicated depressed inpatients, who had a significant improvement after a SD in one night were recruited for this study. The phase advance protocol began on the first day after SD with a bed time from 5:00 p. m. to 12:00 p. m. on the first, from 7:00 p. m. to 2:00 a. m. on the second and 9:00 p. m. to 4:00 a. m. on the third day after SD. Three patients dropped out because of protocol violations. Only ten of the remaining 25 SD responders had a relapse during the three days of phase advance treatment or during the two days after it. Two of the relapsers improved again until day 6, i. e. 68 % showed an improvement of at least 30 % six days after the beginning of the treatment. This study indicates that even a three day phase advance protocol may help to prevent relapses after successful SD. [ABSTRACT FROM AUTHOR] |
| Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 9987792 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Is the antidepressive effect of sleep deprivation stabilized by a three day phase advance of the sleep period?: A pilot study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Voderholzer%2C+U%2E%22">Voderholzer, U.</searchLink><br /><searchLink fieldCode="AR" term="%22Valerius%2C+G%2E%22">Valerius, G.</searchLink><br /><searchLink fieldCode="AR" term="%22Schaerer%2C+L%2E%22">Schaerer, L.</searchLink><br /><searchLink fieldCode="AR" term="%22Riemann%2C+D%2E%22">Riemann, D.</searchLink><br /><searchLink fieldCode="AR" term="%22Giedke%2C+H%2E%22">Giedke, H.</searchLink><br /><searchLink fieldCode="AR" term="%22Schwärzler%2C+F%2E%22">Schwärzler, F.</searchLink><br /><searchLink fieldCode="AR" term="%22Berger%2C+M%2E%22">Berger, M.</searchLink><br /><searchLink fieldCode="AR" term="%22Wiegand%2C+M%2E%22">Wiegand, M.</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Archives+of+Psychiatry+%26+Clinical+Neuroscience%22">European Archives of Psychiatry & Clinical Neuroscience</searchLink>. 2003, Vol. 253 Issue 2, p68. 5p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Sleep+deprivation%22">Sleep deprivation</searchLink><br /><searchLink fieldCode="DE" term="%22Insomnia%22">Insomnia</searchLink><br /><searchLink fieldCode="DE" term="%22Sleep+disorders%22">Sleep disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Mental+depression%22">Mental depression</searchLink><br /><searchLink fieldCode="DE" term="%22Antidepressants%22">Antidepressants</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Sleep deprivation (SD) induces a rapid amelioration of mood in about 60 % of depressed patients. After the next night of sleep, however, most patients experience a relapse. Previous studies demonstrated that a six day sleep-phase advance protocol prevents relapses in about 60 % of patients who responded positively to SD. We investigated whether also a three day phase advance of the sleep period might be able to maintain the antidepressant effects of SD. Twenty-eight medicated depressed inpatients, who had a significant improvement after a SD in one night were recruited for this study. The phase advance protocol began on the first day after SD with a bed time from 5:00 p. m. to 12:00 p. m. on the first, from 7:00 p. m. to 2:00 a. m. on the second and 9:00 p. m. to 4:00 a. m. on the third day after SD. Three patients dropped out because of protocol violations. Only ten of the remaining 25 SD responders had a relapse during the three days of phase advance treatment or during the two days after it. Two of the relapsers improved again until day 6, i. e. 68 % showed an improvement of at least 30 % six days after the beginning of the treatment. This study indicates that even a three day phase advance protocol may help to prevent relapses after successful SD. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Archives of Psychiatry & Clinical Neuroscience is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00406-003-0408-7 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 68 Subjects: – SubjectFull: Sleep deprivation Type: general – SubjectFull: Insomnia Type: general – SubjectFull: Sleep disorders Type: general – SubjectFull: Mental depression Type: general – SubjectFull: Antidepressants Type: general Titles: – TitleFull: Is the antidepressive effect of sleep deprivation stabilized by a three day phase advance of the sleep period?: A pilot study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Voderholzer, U. – PersonEntity: Name: NameFull: Valerius, G. – PersonEntity: Name: NameFull: Schaerer, L. – PersonEntity: Name: NameFull: Riemann, D. – PersonEntity: Name: NameFull: Giedke, H. – PersonEntity: Name: NameFull: Schwärzler, F. – PersonEntity: Name: NameFull: Berger, M. – PersonEntity: Name: NameFull: Wiegand, M. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 04 Text: 2003 Type: published Y: 2003 Identifiers: – Type: issn-print Value: 09401334 Numbering: – Type: volume Value: 253 – Type: issue Value: 2 Titles: – TitleFull: European Archives of Psychiatry & Clinical Neuroscience Type: main |
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