Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer's Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial.

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Title: Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer's Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled, 78-Week APOLLOE4 Trial.
Authors: Abushakra, Susan1 (AUTHOR) susan.abushakra@alzheon.com, Power, Aidan1 (AUTHOR), Watson, David2 (AUTHOR), Porsteinsson, Anton3 (AUTHOR), Sabbagh, Marwan4 (AUTHOR), MacSweeney, Emer5 (AUTHOR), Cohen, Sharon6 (AUTHOR), Boada Rovira, Mercè7 (AUTHOR), Doraiswamy, P. Murali8 (AUTHOR), Liang, Earvin1 (AUTHOR), Flint, Susan1 (AUTHOR), Kesslak, J. Patrick1 (AUTHOR), McLaine, Rosalind1 (AUTHOR), Albayrak, Adem1 (AUTHOR), Schaefer, Jean1 (AUTHOR), Yu, Jeremy1 (AUTHOR), Tolar, Luke1 (AUTHOR), Dickson, Sam9 (AUTHOR), Hey, John A.1 (AUTHOR), Tolar, Martin1 (AUTHOR)
Source: Drugs. Nov2025, Vol. 85 Issue 11, p1455-1472.
Database: SPORTDiscus with Full Text
Description
ISSN:00126667
DOI:10.1007/s40265-025-02250-5