Bibliographic Details
| Title: |
Short-term air pollution exposure decreases lung function: a repeated measures study in healthy adults. |
| Authors: |
Panis, Luc Int1,2 luc.intpanis@vito.be, Provost, Eline B.1,3, Cox, Bianca3, Louwies, Tijs1,3, Laeremans, Michelle1,2, Standaert, Arnout1, Dons, Evi1,3, Holmstock, Luc4, Nawrot, Tim3,5, De Boever, Patrick1,3, Int Panis, Luc2,6 (AUTHOR) |
| Source: |
Environmental Health: A Global Access Science Source. 6/14/2017, Vol. 16, p1-7. 7p. 3 Charts, 1 Graph. |
| Subject Terms: |
*Physiological effects of air pollution, *Particulate matter, *Ozone, *Nitrogen oxides, *Air pollution, *Environmental exposure, Pulmonary function tests, Spirometry, Lung physiology, Longitudinal method, Lungs, Retrospective studies |
| Geographic Terms: |
Belgium |
| Abstract: |
Background: Daily changes in ambient concentrations of particulate matter, nitrogen oxides and ozone are associated with increased cardiopulmonary morbidity and mortality, with the lungs and their function being a vulnerable target.Methods: To evaluate the association between daily changes in air pollution and lung function in healthy adults we obtained annual lung function measurements from a routine worker health surveillance program not designed for research purposes. Forced Vital Capacity (FVC), Forced Expiratory Volume in the first second (FEV1), FEV1/FVC and Peak Expiratory flow (PEF) from a cohort of 2449 employees were associated with daily measurements of PM10, NO2 and ozone at a nearby monitoring station in the North of Belgium. Repeated measures were available for the period 2011-2015.Results: The mean (SD) PM10 concentration on the day of the lung function test was 24.9 (15.5) μg/m3. A 10 μg PM10/m3 increase on the day of the clinical examination was associated with a 18.9 ml lower FVC (95% CI: -27.5 to -10.3, p < 0.0001), 12.8 ml lower FEV1 (-19.1 to -6.5; p < 0.0001), and a 51.4 ml/s lower PEF (-75.0 to -27.0; p < 0.0001). The FEV1/FVC-ratio showed no associations. An increase of 10 μgNO2/m3 was associated with a reduction in PEF (-66.1 ml/s (-106.6 to -25.6; p < 0.001)) on the day of the examination.Conclusions: We found negative associations between daily variations in ambient air pollution and FVC, FEV1 and PEF in healthy adults. [ABSTRACT FROM AUTHOR] |
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| Database: |
GreenFILE |
