Application of Fucoxanthin‐Loaded Probiotic Membrane Vesicles in Dietary Intervention of High‐Fat Diet Induced Obese Mice and Color Improvement for Fruit Juice.
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| Title: | Application of Fucoxanthin‐Loaded Probiotic Membrane Vesicles in Dietary Intervention of High‐Fat Diet Induced Obese Mice and Color Improvement for Fruit Juice. |
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| Authors: | Liang, Duo1 (AUTHOR), Sun, Yueling1 (AUTHOR), Wu, Jinfeng1 (AUTHOR), Liu, Ziling1 (AUTHOR), Lin, Rong1 (AUTHOR), Jin, Ritian1 (AUTHOR), Yang, Shen1 (AUTHOR) yangshen@jmu.edu.cn |
| Source: | Food Science & Nutrition. Mar2026, Vol. 14 Issue 3, p1-14. 14p. |
| Subject Terms: | Prevention of obesity, Food color, Gut microbiota, Functional foods, Carotenoids, High-fat diet, Extracellular vesicles |
| Abstract: | Development of nano‐encapsulated bioactive compounds as nutritional interventions and food‐grade additives presents a critical pathway for advancing translational applications in functional food development and health sciences. This study validates the dual efficacy of fucoxanthin‐loaded probiotic membrane vesicles (FX‐MVs) as both a nutritional intervention for high‐fat diet‐induced obesity and a natural pigment for food applications. The results demonstrated that FX‐MVs significantly suppressed body weight gain, decreased the ratio of white adipose tissue, and reduced serum and hepatic lipid levels in mice. Meanwhile, FX‐MVs reshaped the gut microbiota composition and enhanced microbial homeostasis. Furthermore, FX‐MVs application markedly improved the color attributes of fresh apple juice and preserved its original flavor profile, without introducing undesirable olfactory or gustatory notes. This work provided novel insights into fucoxanthin‐loaded probiotic membrane vesicles as effective nutrition components in obesity intervention and natural colorant in food systems, demonstrating synergistic potential in both nutraceutical and technological applications. [ABSTRACT FROM AUTHOR] |
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| Database: | GreenFILE |
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| Abstract: | Development of nano‐encapsulated bioactive compounds as nutritional interventions and food‐grade additives presents a critical pathway for advancing translational applications in functional food development and health sciences. This study validates the dual efficacy of fucoxanthin‐loaded probiotic membrane vesicles (FX‐MVs) as both a nutritional intervention for high‐fat diet‐induced obesity and a natural pigment for food applications. The results demonstrated that FX‐MVs significantly suppressed body weight gain, decreased the ratio of white adipose tissue, and reduced serum and hepatic lipid levels in mice. Meanwhile, FX‐MVs reshaped the gut microbiota composition and enhanced microbial homeostasis. Furthermore, FX‐MVs application markedly improved the color attributes of fresh apple juice and preserved its original flavor profile, without introducing undesirable olfactory or gustatory notes. This work provided novel insights into fucoxanthin‐loaded probiotic membrane vesicles as effective nutrition components in obesity intervention and natural colorant in food systems, demonstrating synergistic potential in both nutraceutical and technological applications. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 20487177 |
| DOI: | 10.1002/fsn3.71686 |
