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Structure-optimization and structure-activity relationship of diphenylpyrazinyl aminoalkoxyacetic acid derivatives: piperidine substitution and hydrophobic modification as key strategies for IP receptor agonists.

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Bibliographic Details
Title:	Structure-optimization and structure-activity relationship of diphenylpyrazinyl aminoalkoxyacetic acid derivatives: piperidine substitution and hydrophobic modification as key strategies for IP receptor agonists.
Authors:	Cai, Xianrong¹, Gao, Liyan¹, Cheng, Juping¹, Wang, Yuhe¹, Liu, Guiying¹, Ma, Xiaoyan¹, Fu, Qingquan¹, Lu, Jingguang¹, An, Xiaoli¹, Anxl23@suse.edu.cn, Mu, Zhenqiang², 10976@cqmpc.edu.cn
Source:	Journal of Computer-Aided Molecular Design; 7/23/2026, Vol. 40 Issue 1, p1-12, 12p
Database:	Applied Science & Technology Source

Description
ISSN:	0920654X
DOI:	10.1007/s10822-026-00886-3