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Lead Optimization and Modulationof hERG Activityin a Series of Aminooxazoline Xanthene β-Site AmyloidPrecursor Protein Cleaving Enzyme (BACE1) Inhibitors.

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Bibliographic Details
Title: Lead Optimization and Modulationof hERG Activityin a Series of Aminooxazoline Xanthene β-Site AmyloidPrecursor Protein Cleaving Enzyme (BACE1) Inhibitors.
Authors: Epstein, Oleg1, Bryan, Marian C.1, Cheng, Alan C.1, Derakhchan, Katayoun1, Dineen, Thomas A.1, Hickman, Dean1, Hua, Zihao1, Human, Jason B.1, Kreiman, Charles1, Marx, Isaac E.1, Weiss, Matthew M.1, Wahl, Robert C.1, Wen, Paul H.1, Whittington, Douglas A.1, Wood, Stephen1, Zheng, Xiao Mei1, Fremeau, Robert T.1, White, Ryan D.1, Patel, Vinod F.1
Source: Journal of Medicinal Chemistry. Dec2014, Vol. 57 Issue 23, p9796-9810. 15p.
Database: Academic Search Ultimate
Description
ISSN:00222623
DOI:10.1021/jm501266w