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Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome.

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Title: Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome.
Authors: Rzepecka, Justyna1 justyna.rzepecka@aquila-bm.com, Pineda, Miguel A.2 Miguel.Pineda@glasgow.ac.uk, Al-Riyami, Lamyaa1 Lamyaa.alriyami@gmail.com, Rodgers, David T.2 david.t.rodgers@googlemail.com, Huggan, Judith K.3 j.huggan@strath.ac.uk, Lumb, Felicity E.1 felicity.lumb@strath.ac.uk, Khalaf, Abedawn I.3 abedawn.khalaf@strath.ac.uk, Meakin, Paul J.4 p.j.meakin@dundee.ac.uk, Corbet, Marlene2 m.corbet.1@research.gla.ac.uk, Ashford, Michael L.4 m.l.j.ashford@dundee.ac.uk, Suckling, Colin J.3 c.j.suckling@strath.ac.uk, Harnett, Margaret M.2 Margaret.Harnett@glasgow.ac.uk, Harnett, William1 w.harnett@strath.ac.uk
Source: Journal of Autoimmunity. Jun2015, Vol. 60, p59-73. 15p.
Database: Academic Search Ultimate
Description
ISSN:08968411
DOI:10.1016/j.jaut.2015.04.005