Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain.

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Title: Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain.
Authors: Wang, Kai1,2,3, Xu, Ruijuan1,2, Schrandt, Jennifer1,2, Shah, Prithvi4,5, Gong, Yong Z.6, Preston, Chet4, Wang, Louis4, Yi, Jae Kyo1,2, Lin, Chih-Li1,2, Sun, Wei6, Spyropoulos, Demetri D.6, Rhee, Soyoung6, Li, Mingsong7, Zhou, Jie3, Ge, Shaoyu6, Zhang, Guofeng8, Snider, Ashley J.1,2,9, Hannun, Yusuf A.1,2, Obeid, Lina M.1,2,9, Mao, Cungui1,2 cungui.mao@stonybrook.edu
Source: PLoS Genetics. 10/16/2015, Vol. 11 Issue 10, p1-31. 31p.
Database: Academic Search Ultimate
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ISSN:15537390
DOI:10.1371/journal.pgen.1005591