Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.
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| Title: | Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists. |
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| Authors: | Seow, Vernon1, Lim, Junxian, Cotterell, Adam J.1, Yau, Mei-Kwan, Xu, Weijun, Lohman, Rink-Jan, Kok, W. Mei, Stoermer, Martin J.1, Sweet, Matthew J., Reid, Robert C., Suen, Jacky Y., Fairlie, David P. |
| Source: | Scientific Reports. 4/22/2016, p24575. 1p. |
| Database: | Academic Search Ultimate |
| ISSN: | 20452322 |
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| DOI: | 10.1038/srep24575 |
