Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.
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| Title: | Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists. |
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| Authors: | Seow, Vernon1, Lim, Junxian, Cotterell, Adam J.1, Yau, Mei-Kwan, Xu, Weijun, Lohman, Rink-Jan, Kok, W. Mei, Stoermer, Martin J.1, Sweet, Matthew J., Reid, Robert C., Suen, Jacky Y., Fairlie, David P. |
| Source: | Scientific Reports. 4/22/2016, p24575. 1p. |
| Database: | Academic Search Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: asn DbLabel: Academic Search Ultimate An: 114756404 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=114756404 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/srep24575 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: 24575 Titles: – TitleFull: Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Seow, Vernon – PersonEntity: Name: NameFull: Lim, Junxian – PersonEntity: Name: NameFull: Cotterell, Adam J. – PersonEntity: Name: NameFull: Yau, Mei-Kwan – PersonEntity: Name: NameFull: Xu, Weijun – PersonEntity: Name: NameFull: Lohman, Rink-Jan – PersonEntity: Name: NameFull: Kok, W. Mei – PersonEntity: Name: NameFull: Stoermer, Martin J. – PersonEntity: Name: NameFull: Sweet, Matthew J. – PersonEntity: Name: NameFull: Reid, Robert C. – PersonEntity: Name: NameFull: Suen, Jacky Y. – PersonEntity: Name: NameFull: Fairlie, David P. IsPartOfRelationships: – BibEntity: Dates: – D: 22 M: 04 Text: 4/22/2016 Type: published Y: 2016 Identifiers: – Type: issn-print Value: 20452322 Titles: – TitleFull: Scientific Reports Type: main |
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