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Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors.

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Bibliographic Details
Title: Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors.
Authors: Barlaam, Bernard1 bernard.barlaam2@astrazeneca.com, Cosulich, Sabina1, Fitzek, Martina2, Germain, Hervé3, Green, Stephen2, Hanson, Lyndsey L.2, Harris, Craig S.3, Hancox, Urs2, Hudson, Kevin2, Lambert-van der Brempt, Christine3, Lamorlette, Maryannick3, Magnien, Françoise3, Ouvry, Gilles3, Page, Ken2, Ruston, Linette2, Ward, Lara2, Delouvrié, Bénédicte3
Source: Bioorganic & Medicinal Chemistry Letters. Jul2017, Vol. 27 Issue 13, p3030-3035. 6p.
Database: Academic Search Ultimate
Description
ISSN:0960894X
DOI:10.1016/j.bmcl.2017.05.028