Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation.
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| Title: | Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of Neuroinflammation. |
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| Authors: | McAllister, Laura A.1 laura.mcallister@pfizer.com, Butler, Christopher R.1, Mente, Scot1, O'Neil, Steven V.2, Fonseca, Kari R.1, Piro, Justin R.1, Cianfrogna, Julie A.2, Foley, Timothy L.2, Gilbert, Adam M.2, Harris, Anthony R.2, Helal, Christopher J.2, Johnson, Douglas S.1, Montgomery, Justin I.2, Nason, Deane M.2, Noell, Stephen2, Pandit, Jayvardhan2, Rogers, Bruce N.1, Samad, Tarek A.1, Shaffer, Christopher L.1, Silva, Rafael G. da2 |
| Source: | Journal of Medicinal Chemistry. 4/12/2018, Vol. 61 Issue 7, p3008-3026. 19p. |
| Database: | Academic Search Ultimate |
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