Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation.
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| Title: | Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation. |
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| Authors: | Yan, Qi1, Chen, Yuzhe2,3, Tang, Baiyou2,4, Xiao, Qiang1, Qu, Rong2,3, Tong, Linjiang2, Liu, Jian1, Ding, Jian2, Chen, Yi2, Ding, Ning1, Tan, Wenfu1 wftan@fudan.edu.cn, Xie, Hua2 hxie@simm.ac.cn, Li, Yingxia1 liyx417@fudan.edu.cn |
| Source: | European Journal of Medicinal Chemistry. May2018, Vol. 152, p298-306. 9p. |
| Database: | Academic Search Ultimate |
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