Lack of Impact by SCY‐078, a First‐in‐Class Oral Fungicidal Glucan Synthase Inhibitor, on the Pharmacokinetics of Rosiglitazone, a Substrate for CYP450 2C8, Supports the Low Risk for Clinically Relevant Metabolic Drug‐Drug Interactions

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Title: Lack of Impact by SCY‐078, a First‐in‐Class Oral Fungicidal Glucan Synthase Inhibitor, on the Pharmacokinetics of Rosiglitazone, a Substrate for CYP450 2C8, Supports the Low Risk for Clinically Relevant Metabolic Drug‐Drug Interactions
Authors: Wring, Stephen1, Murphy, Gail2, Atiee, George3, Corr, Christy4, Hyman, Michele4, Willett, Michael5, Angulo, David1 David.angulo@scynexis.com
Source: Journal of Clinical Pharmacology. Oct2018, Vol. 58 Issue 10, p1305-1313. 9p.
Database: Academic Search Ultimate
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ISSN:00912700
DOI:10.1002/jcph.1146