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Discovery of N-(piperidin-3-yl)-N-(pyridin-2-yl)piperidine/piperazine-1-carboxamides as small molecule inhibitors of PCSK9.

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Bibliographic Details
Title: Discovery of N-(piperidin-3-yl)-N-(pyridin-2-yl)piperidine/piperazine-1-carboxamides as small molecule inhibitors of PCSK9.
Authors: Londregan, Allyn T.1 allyn.t.londregan@pfizer.com, Aspnes, Gary1, Limberakis, Chris1, Loria, Paula M.1, McClure, Kim F.1, Petersen, Donna N.1, Raymer, Brian1, Ruggeri, Roger B.1, Wei, Liuqing1, Xiao, Jun1, Piotrowski, David W.1
Source: Bioorganic & Medicinal Chemistry Letters. Dec2018, Vol. 28 Issue 23/24, p3685-3688. 4p.
Database: Academic Search Ultimate
Description
ISSN:0960894X
DOI:10.1016/j.bmcl.2018.10.029