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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.

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Title: From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.
Authors: Petrilli, Whitney L.1 (AUTHOR) whitney_petrilli@merck.com, Adam, Gregory C.1,2 (AUTHOR) gregory_adam@merck.com, Erdmann, Roman S.1,3 (AUTHOR) roman.erdmann@merck.com, Abeywickrema, Pravien4 (AUTHOR), Agnani, Vijayalakshmi5 (AUTHOR), Ai, Xi6 (AUTHOR), Baysarowich, Jen5 (AUTHOR), Byrne, Noel4 (AUTHOR), Caldwell, John P.1 (AUTHOR), Chang, Wonsuk1 (AUTHOR), DiNunzio, Edward5 (AUTHOR), Feng, Zhe1 (AUTHOR), Ford, Rachael4 (AUTHOR), Ha, Sookhee7 (AUTHOR), Huang, Yongcheng6 (AUTHOR), Hubbard, Brian6 (AUTHOR), Johnston, Jennifer M.4 (AUTHOR), Kavana, Michael5 (AUTHOR), Lisnock, Jean-Marie5 (AUTHOR), Liang, Rui1 (AUTHOR)
Source: Cell Chemical Biology. Jan2020, Vol. 27 Issue 1, p32-32. 1p.
Database: Academic Search Ultimate
Description
ISSN:24519456
DOI:10.1016/j.chembiol.2019.10.002