Identification of De Novo Pyrimidine Synthesis as a Targetable Vulnerability in a Novel IDH1 Mutant Engineered Astrocytoma Model.

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Bibliographic Details
Title: Identification of De Novo Pyrimidine Synthesis as a Targetable Vulnerability in a Novel IDH1 Mutant Engineered Astrocytoma Model.
Authors: Shi, D.D.1 (AUTHOR), Wang, A.C.2 (AUTHOR), Gao, W.2 (AUTHOR), Khanal, J.2 (AUTHOR), Levitt, M.M.3 (AUTHOR), Jennings, R.B.2,4 (AUTHOR), Signoretti, S.2,4 (AUTHOR), Nguyen, Q.D.5 (AUTHOR), Endress, J.E.6,7 (AUTHOR), Xu, M.3 (AUTHOR), Gradl, S.8 (AUTHOR), Sutter, A.8 (AUTHOR), Jeffers, M.9 (AUTHOR), Janzer, A.8 (AUTHOR), Cahill, D.P.10 (AUTHOR), Abdullah, K.G.11 (AUTHOR), Ligon, K.L.12,13 (AUTHOR), Harris, I.S.14 (AUTHOR), Kaelin, W.G.2,15 (AUTHOR), McBrayer, S.K.3 (AUTHOR)
Source: International Journal of Radiation Oncology, Biology, Physics. 2021 Supplement, Vol. 111 Issue 3, pS86-S86. 1p.
Database: Academic Search Ultimate
Description
ISSN:03603016
DOI:10.1016/j.ijrobp.2021.07.205