Development of potent dual PDK1/AurA kinase inhibitors for cancer therapy: Lead-optimization, structural insights, and ADME-Tox profile.
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| Title: | Development of potent dual PDK1/AurA kinase inhibitors for cancer therapy: Lead-optimization, structural insights, and ADME-Tox profile. |
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| Authors: | Sestito, Simona1 (AUTHOR), Bacci, Andrea1 (AUTHOR), Chiarugi, Sara2,3 (AUTHOR), Runfola, Massimiliano1 (AUTHOR), Gado, Francesca1 (AUTHOR), Margheritis, Eleonora2 (AUTHOR), Gul, Sheraz4,5 (AUTHOR), Riveiro, Maria E.1,6 (AUTHOR) eugenia.riveiro@e2dg.com, Vazquez, Ramiro6 (AUTHOR), Huguet, Samuel7 (AUTHOR), Manera, Clementina1 (AUTHOR), Rezai, Keyvan7 (AUTHOR), Garau, Gianpiero1,2 (AUTHOR) gianpiero.garau@iit.it, Rapposelli, Simona1,8 (AUTHOR) simona.rapposelli@unipi.it |
| Source: | European Journal of Medicinal Chemistry. Dec2021, Vol. 226, pN.PAG-N.PAG. 1p. |
| Database: | Academic Search Ultimate |
| ISSN: | 02235234 |
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| DOI: | 10.1016/j.ejmech.2021.113895 |
