CeRebrUm and CardIac Protection with ALlopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL): study protocol of a phase III, randomized, quadruple-blinded, placebo-controlled, Dutch multicenter trial.
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| Title: | CeRebrUm and CardIac Protection with ALlopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL): study protocol of a phase III, randomized, quadruple-blinded, placebo-controlled, Dutch multicenter trial. |
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| Authors: | Stegeman, Raymond1,2,3,4,5 (AUTHOR), Nijman, Maaike1,2,5 (AUTHOR), Breur, Johannes M. P. J.2 (AUTHOR), Groenendaal, Floris1,5 (AUTHOR), Haas, Felix4 (AUTHOR), Derks, Jan B.6 (AUTHOR), Nijman, Joppe3 (AUTHOR), van Beynum, Ingrid M.7 (AUTHOR), Taverne, Yannick J. H. J.8 (AUTHOR), Bogers, Ad J. J. C.8 (AUTHOR), Helbing, Willem A.7,9 (AUTHOR), de Boode, Willem P.10 (AUTHOR), Bos, Arend F.11 (AUTHOR), Berger, Rolf M. F.12 (AUTHOR), Accord, Ryan E.13 (AUTHOR), Roes, Kit C. B.14 (AUTHOR), de Wit, G. Ardine15 (AUTHOR), Jansen, Nicolaas J. G.3,16 (AUTHOR), Benders, Manon J. N. L.1 (AUTHOR) M.Benders@umcutrecht.nl, CRUCIAL trial consortium (CORPORATE AUTHOR) |
| Source: | Trials. 2/23/2022, Vol. 23 Issue 1, p1-15. 15p. 1 Diagram, 3 Charts. |
| Database: | Academic Search Ultimate |
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| ISSN: | 17456215 |
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| DOI: | 10.1186/s13063-022-06098-y |
