A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models.

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Bibliographic Details
Title: A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models.
Authors: Singh, Dharaminder1 (AUTHOR) Dharaminder.Singh@CN-Bio.com, Deosarkar, Sudhir P.2 (AUTHOR), Cadogan, Elaine3 (AUTHOR), Flemington, Vikki3 (AUTHOR), Bray, Alysha1 (AUTHOR), Zhang, Jingwen4 (AUTHOR), Reiserer, Ronald S.5 (AUTHOR), Schaffer, David K.5 (AUTHOR), Gerken, Gregory B.5 (AUTHOR), Britt, Clayton M.5 (AUTHOR), Werner, Erik M.5 (AUTHOR), Gibbons, Francis D.6 (AUTHOR), Kostrzewski, Tomasz1 (AUTHOR), Chambers, Christopher E.3 (AUTHOR), Davies, Emma J.3 (AUTHOR), Montoya, Antonio Ramos3 (AUTHOR), Fok, Jacqueline H. L.3 (AUTHOR), Hughes, David1 (AUTHOR), Fabre, Kristin7 (AUTHOR), Wagoner, Matthew P.2 (AUTHOR)
Source: PLoS Biology. 5/26/2022, Vol. 20 Issue 5, p1-17. 17p. 1 Diagram, 4 Graphs.
Database: Academic Search Ultimate
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