Application of SHAP values for inferring the optimal functional form of covariates in pharmacokinetic modeling.

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Title: Application of SHAP values for inferring the optimal functional form of covariates in pharmacokinetic modeling.
Authors: Janssen, Alexander1 (AUTHOR) a.janssen@amsterdamumc.nl, Hoogendoorn, Mark2 (AUTHOR), Cnossen, Marjon H.3 (AUTHOR), Mathôt, Ron A. A.1 (AUTHOR) r.mathot@amsterdamumc.nl, Cnossen, M. H. (AUTHOR), Reitsma, S. H. (AUTHOR), Leebeek, F. W. G. (AUTHOR), Mathôt, R. A. A. (AUTHOR), Fijnvandraat, K. (AUTHOR), Coppens, M. (AUTHOR), Meijer, K. (AUTHOR), Schols, S. E. M. (AUTHOR), Eikenboom, H. C. J. (AUTHOR), Schutgens, R. E. G. (AUTHOR), Beckers, E. A. M. (AUTHOR), Ypma, P. (AUTHOR), Kruip, M. J. H. A. (AUTHOR), Polinder, S. (AUTHOR), Tamminga, R. Y. J. (AUTHOR), Brons, P. (AUTHOR)
Source: CPT: Pharmacometrics & Systems Pharmacology. Aug2022, Vol. 11 Issue 8, p1100-1110. 11p.
Database: Academic Search Ultimate
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ISSN:21638306
DOI:10.1002/psp4.12828